Protein Alignment ACXE and Npr2

DIOPT Version :9

• Sequence 1: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: NP_446290.1
• Gene: Npr2 / 116564
• RGDID: 620851
• Length: 1047
• Species: Rattus norvegicus
• Alignment Length: 1174
• Identity: 237/1174 - (20%)
• Similarity: 403/1174 - (34%)
• Gaps: 374/1174 - (31%)

  Fly    63 CALLLATIERRSI-IYFDVALSIGCALVLILVLSVNFCDEFIAKHTWYM------YASSIFAS-- 118
            |:..||.:....: :|.|..|.:|...|........|     |.| |::      ..:|.||:
  Rat    75 CSEYLAPLRAVDLKLYHDPDLLLGPGCVYPAASVARF-----ASH-WHLPLLTAGAVASGFAAKN 133

  Fly   119 ---LTLV-----FADLTESIYHTYAH-SWILGTFYDTYIIYMIYMFL-----PIHFISGAVLLAL 169
               .|||     ...|.|.:...:.| :|       |....::|:..     |.:|....|..||
  Rat   134 EHYRTLVRTGPSAPKLGEFVVTLHGHFNW-------TARAALLYLDARTDDRPHYFTIEGVFEAL 191

  Fly   170 LVSGLYILYFVIFIAQGFAQFASALFSVGGMSV------DIVHYLCL-----NLVGIFYRVMNDT 223
            ..|.|.:.:.|.....|..:.|:......|..|      :::|.:.|     ||....|......
  Rat   192 QGSNLSVQHQVYTREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLD 256

  Fly   224 VVRSSFLDRHQYIKEKIWLRNARLQEKQLL----DSIL------PPQISLPLQKDIQGRIVMAKQ 278
            |...|..........:.|..|...::.|.|    .::|      ||.   |..::.|.|:::..:
  Rat   257 VFGESLRAGPTRATGRPWQDNRTQEQAQALREAFQTVLVITYREPPN---PEYQEFQNRLLIRAR 318

  Fly   279 GIHSWTAMERTMAIQIHP-----------DVSILYADVVNYT----------------------H 310
                     ....:::.|           |..:|||.|:|.|                      |
  Rat   319 ---------EDFGVELAPSLMNLIAGCFYDGILLYAQVLNETIQEGGTREDGLRIVEKMQGRRYH 374

  Fly   311 LTTTLTV---------EMLVKVLHDL-YGRFDLAA-YRYKVQRIKFLG------------DCYYC 352
            ..|.|.|         :.::..:.|| .|.|..|| |....::|.:.|            |...|
  Rat   375 GVTGLVVMDKNNDRETDFVLWAMGDLESGDFQPAAHYSGAEKQIWWTGRPIPWVKGAPPLDNPPC 439

  Fly   353 VAGLSDPDPDHA--NNCVILGLSM-INHIMEVRDIHGLDINMRIGVHSGNLFAGVIGEAKLQFDI 414
            ...|.||..|..  :...|:.|.. |..||             .||.|..:|..::.|.:|...:
  Rat   440 AFDLDDPSCDKTPLSTLAIVALGTGITFIM-------------FGVSSFLIFRKLMLEKELASML 491

  Fly   415 WGL---DVTIAN---VLESTGVPGCVHISGATLNNLDVNRFDIEDGPEEARDHPLLKKYRIRSYI 473
            |.:   ::...|   ..:..|....:.:.|::..:|....                .||:|.:
  Rat   492 WRIRWEELQFGNSDRYHKGAGSRLTLSLRGSSYGSLMTAH----------------GKYQIFA-- 538

  Fly   474 IRQDLHMDDEDSDEFLGDLHSISLCNMGAQPRISDSANQSLRALFHEELRE-EFRKMPVSAFSPK 537
                      ::..|.|::.:|...|   :.|| :...|.|..|.|  :|: :|..:       .
  Rat   539 ----------NTGHFKGNVVAIKHVN---KKRI-ELTRQVLFELKH--MRDVQFNHL-------T 580

  Fly   538 RLLGICRFNTGKEVPAHQNLNICLT-------FTDPILERAYLKQTDYMYKYSIILSASVGCSLV 595
            |.:|.|     .:.|     |||:.       ....|||...: ..|:|::||:|.....|.:.:
  Rat   581 RFIGAC-----IDPP-----NICIVTEYCPRGSLQDILENDSI-NLDWMFRYSLINDLVKGMAFL 634

  Fly   596 YIELMDT--QMICSSC-----FVLPASVATIQCILALI------AWYKKYCWTRYGRNNVPHHYN 647
            :..::.:  .:..|:|     |||..:...:....:..      |.|.|..||      .|...:
  Rat   635 HNSIISSHGSLKSSNCVVDSRFVLKITDYGLASFRSTAEPDDSHALYAKKLWT------APELLS 693

  Fly   648 GFSCFIFRIHDKILNSLPI----RICIYLFLMISSFFVMCLIVMSCQREEFEMAYIE-------E 701
            |             |.||.    :..:|.|.:|       |..::.:...|   |:|       |
  Rat   694 G-------------NPLPTTGMQKADVYSFAII-------LQEIALRSGPF---YLEGLDLSPKE 735

  Fly   702 RLFHYEQEAHICFHPWVTTNMLS--LMICLTFTFAHIPI------MVKTAVAILETLAYLLLIFF 758
            .:..........|.|.:....|:  |::.:...:|..|.      .:|..:.
  Rat   736 IVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPTERPDFGQIKGFIR------------- 787

  Fly   759 QFDFVFHHSVTTNPYFKSE-YAHALLICITFLIMFVKERQIEFTNKVNFNWRVDLRKEENAASLT 822
            :|:.....|:..|...:.| ||:.|            |:.:|...:.   :..:.||.|
  Rat   788 RFNKEGGTSILDNLLLRMEQYANNL------------EKLVEERTQA---YLEEKRKAE------ 831

  Fly   823 NHSIIIILNNILPSHIVDVYLNSLAKHE-LYFENYRMVSVMFAMLINF------EMDLRSLRVLN 880
                 .:|..|||..:.:    .|.:.| :..|.:..|::.|:.::.|      ...::.:.:||
  Rat   832 -----ALLYQILPHSVAE----QLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLN 887

  Fly   881 EIIAEFDTLLLFYKEYYTVEKIKIVGCTYMAACGLDLNFAGSTSTNRKESIPPTEFNEEQSRRIL 945
            ::...||.::    :.:.|.|::.:|..||...||       ...|.:...|      |.:|..|
  Rat   888 DLYTCFDAII----DNFDVYKVETIGDAYMVVSGL-------PGRNGQRHAP------EIARMAL 935

  Fly   946 FQQSNEDLDEVVFVMTSYAL-----DMMRTLAKSNEAYQSIAGDRNITDGTIAIGISSGEVMAGI 1005
            ..     ||.|    :|:.:     |.:|                      :.||:.:|.|.||:
  Rat   936 AL-----LDAV----SSFRIRHRPHDQLR----------------------LRIGVHTGPVCAGV 969

  Fly  1006 VGASQPHYDIWGNPVNMASRMESTGLPGHIHVTEETSEILQQFG-ITCSYRGMTFVKGRGKIPTY 1069
            ||...|.|.::|:.||.||||||.|....|||:..|.:.|.:.| .....||...:||:||:.||
  Rat   970 VGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQLELRGDVEMKGKGKMRTY 1034

  Fly  1070 -LVG 1072
             |:|
  Rat  1035 WLLG 1038

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AC_N	<31..272	CDD:318454	52/252 (21%)
		Nucleotidyl_cyc_III	290..459	CDD:325147	43/233 (18%)
		Nucleotidyl_cyc_III	851..1071	CDD:325147	60/232 (26%)
Npr2	NP_446290.1	PBP1_NPR_B	26..421	CDD:380607	73/370 (20%)
		PK_GC-A_B	518..792	CDD:270944	64/367 (17%)
		HNOBA	<798..846	CDD:400168	14/77 (18%)
		CYCc	825..1009	CDD:214485	59/246 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900