Protein Alignment ACXE and npr1

DIOPT Version :10

• Sequence 1: NP_652601.3
• Gene: ACXE / 53426
• FlyBaseID: FBgn0040506
• Length: 1123
• Species: Drosophila melanogaster
• Sequence 2: XP_031747254.1
• Gene: npr1 / 100492092
• XenbaseID: XB-GENE-970522
• Length: 1053
• Species: Xenopus tropicalis
• Alignment Length: 913
• Identity: 181/913 - (19%)
• Similarity: 307/913 - (33%)
• Gaps: 332/913 - (36%)

  Fly   284 TAMERTMAIQIHPDVSILYADVVNYTHL-------TTTLTVEM----------LVKV-------- 323
            :.:...::...|..| :|||..||.|..       .:.:|..|          .||:
 Frog   334 STLMNALSASFHDSV-LLYAHAVNETRANGYSMKNASAVTSYMRNKSFYGASGFVKIDDNGDREN 397

  Fly   324 ---LHDLY---GRFDLAAYRY-----KV-----QRIKFLG-----DCYYCVAGLSDPDPDHANNC 367
               |.|:|   |.|.: .|.|     |:     :.|::.|     |...|....|||      .|
 Frog   398 DFSLWDMYEPHGTFQI-VYNYNGTLRKIVPLPGREIEWPGNRIPRDVPPCGFDHSDP------KC 455

  Fly   368 VILGLSMINHIMEVRDIHGLDINMRIGVHSGNLFAGVIGEAKLQFDIWGL---DVTIANV---LE 426
            .....:    |:|:..|....|.:.|.|.|..::..:..|.:|..::|.:   |:..:|:   |.
 Frog   456 KKSSFT----ILEILSIVICFILLIITVSSIFIYRKLRLEKELAAELWRIRWEDIHTSNLEKNLR 516

  Fly   427 STGVPGCVHISGATLNNL--DVNRFDI------EDGPEEARDHPLLKKYRIRSYIIRQDLHMDDE 483
            ..|....:.:.|:...:|  ...:|.|      ..|...|..|...|:..:...::.:..||.|.
 Frog   517 RAGSKLTLSLRGSNYGSLLTTEGQFQIYAKTAYYKGNIIAVKHINRKRIELTRKVLFELKHMRDV 581

  Fly   484 DSDEFLGDLHSISLCNMGAQPRISDSANQSLRALFHEELREEFRKMPVSAFSPKRLLGICRFNTG 548
            .::..                                                .|.:|.|
 Frog   582 QNEHL------------------------------------------------TRFVGSC----- 593

  Fly   549 KEVPAHQNLNIC-LTFTDP------ILERAYLKQTDYMYKYSIILSASVGCSLVYIELMDT--QM 604
            .:.|     ||| ||...|      |||...: ..|:|::||:|.....|...::..::.|  .:
 Frog   594 IDPP-----NICILTEYCPRGSLQDILENESI-TLDWMFRYSLINDIVKGMLFLHNSVIVTHGNL 652

  Fly   605 ICSSC-----FVLPAS---VATIQC---ILALIAWYKKYCWT---------------------RY 637
            ..|:|     |||..:   :|:.:|   ...:.|::.|..||                     .:
 Frog   653 KSSNCVVDSRFVLKITDYGLASFRCSPDSEDIHAYFAKKLWTSPELLRMETPPPQGTQKGDVYSF 717

  Fly   638 G--------RNNVPHHYNG-FSC--FIFRIHDKILNSLPI-RICIYLFLMISSFFVMCLIVMSC- 689
            |        ||.|.:..|. :|.  .|.|:..:   ..|| |.|..|:..|..   :..::..|
 Frog   718 GIILQEVALRNGVFYVDNADYSPKEIIERVRSR---EKPIFRPCTNLYCHIQE---LGQLMQRCW 776

  Fly   690 -----QREEFEMAYIEERLFHYEQEAHICFHPWVTTNMLSLMICLTFTFAHIPIMVKTAVAILET 749
                 :|.||....::.|.|:.|...:|      ..|:||.|
 Frog   777 AEDPFERPEFNQIKVQLRKFNRESSTNI------LDNLLSRM----------------------- 812

  Fly   750 LAYLLLIFFQFDFVFHHSVTTNPYFKSEYAHALLICITFLIMFVKERQIEFTNKVNFNWRVDLRK 814
                                      .:||:.|            |..:|...:.   :..:.||
 Frog   813 --------------------------EQYANNL------------EELVEDRTQA---YLEEKRK 836

  Fly   815 EENAASLTNHSIIIILNNILPSHIVDVYLNSLAKHE-LYFENYRMVSVMFAMLINF------EMD 872
            .|           .:|..|||..:.:    .|.:.| :..|.:..|::.|:.::.|      ...
 Frog   837 AE-----------ALLYQILPHSVAE----QLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTP 886

  Fly   873 LRSLRVLNEIIAEFDTLLLFYKEYYTVEKIKIVGCTYMAACGLDLNFAGSTSTNRKESIPPTEFN 937
            ::.:.:||::...||.::    :.:.|.|::.:|..||...||                 |....
 Frog   887 MQVVTLLNDLYTCFDAII----DNFDVYKVETIGDAYMVVSGL-----------------PVRNG 930

  Fly   938 EEQSRRILFQQSNEDLDEVVFVMTSYALDMMRTLAKSNEAYQSIAGDRNITDGTIAIGISSGEVM 1002
            :..:|.             |..|:...||.:::....:...|.:         .:.|||.:|.|.
 Frog   931 KLHARE-------------VARMSLALLDAVKSFKIRHRPNQQL---------RLRIGIHTGPVC 973

  Fly  1003 AGIVGASQPHYDIWGNPVNMASRMESTGLPGHIHVTEETSEILQQFG-ITCSYRGMTFVKGRGKI 1066
            ||:||...|.|.::|:.||.||||||.|....|||:..|..:|::|. .....||...:||:||:
 Frog   974 AGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHVSTATHCVLEEFNCFVLELRGDVEMKGKGKV 1038

  Fly  1067 PTY 1069
            .||
 Frog  1039 RTY 1041

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACXE	NP_652601.3	AcyC	65..453	CDD:441717	46/228 (20%)
		Nucleotidyl_cyc_III	290..459	CDD:448371	47/228 (21%)
		Nucleotidyl_cyc_III	851..1071	CDD:448371	57/226 (25%)
npr1	XP_031747254.1	PBP1_NPR_A	27..434	CDD:380608	21/101 (21%)
		PK_GC-A_B	525..799	CDD:270944	62/338 (18%)
		HNOBA	<805..853	CDD:462234	16/126 (13%)
		CYCc	832..1017	CDD:214485	56/242 (23%)