DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alk and EDR1

DIOPT Version :9

Sequence 1:	NP_001261027.1	Gene:	Alk / 53425	FlyBaseID:	FBgn0040505	Length:	1701	Species:	Drosophila melanogaster
Sequence 2:	NP_563824.1	Gene:	EDR1 / 837393	AraportID:	AT1G08720	Length:	933	Species:	Arabidopsis thaliana

Alignment Length:	352	Identity:	101/352 - (28%)
Similarity:	154/352 - (43%)	Gaps:	58/352 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1159 DDSNLNNFNP------NYGCDGILNGHIDVNSL---------PQVARDS-----------LQLVN 1197
            |:|::::...      :.|||..|..|...:|.         |||..|:           |.:..
plant   609 DESHIHDHRKYTSDDISTGCDPRLKDHESTSSSLDSTSYRNDPQVLDDADVGECEIPWNDLVIAE 673

  Fly  1198 ALGKGAFGEVYMALYRHRDGDAVEMGVAVKTLREDPKREKEEDFLKEAAIMAKFNHPNMVHLIGV 1262
            .:|.|::||||     |.|....|:.|. |.|.:|.......:|..|..||.:..|||:|..:|.
plant   674 RIGLGSYGEVY-----HADWHGTEVAVK-KFLDQDFSGAALAEFRSEVRIMRRLRHPNVVFFLGA 732

  Fly  1263 CFDRQPYYIVLELLAGGDLQKFLRENRNTPERPSLLTMKDLLFCALDVAKG--CRYMESKRFIHR 1325
            ........||.|.|..|.|.:.|...::..:....:.|      |||||.|  |.:..:...:||
plant   733 VTRPPNLSIVTEFLPRGSLYRILHRPKSHIDERRRIKM------ALDVAMGMNCLHTSTPTIVHR 791

  Fly  1326 DIAARNCLLSSKGPGRVVKIADFGMSRDIYRSDYYRKGGKAMLPIKWMPPEAFLDGIFTSKTDVW 1390
            |:...|.|:.:...   ||:.|||:|| :..:.:......|..| :||.||...:.....|.||:
plant   792 DLKTPNLLVDNNWN---VKVGDFGLSR-LKHNTFLSSKSTAGTP-EWMAPEVLRNEPSNEKCDVY 851

  Fly  1391 SFGILLWEVFSLGRSPYPGQHNTQVMELV-VRGGRLGSPTECPVSIYKVMADCWNPTPEDRPTFI 1454
            |||::|||:.:| |.|:.|.:..||:..| .:..||..|.|....:.:::.:||...|..||:|.
plant   852 SFGVILWELATL-RLPWRGMNPMQVVGAVGFQNRRLEIPKELDPVVGRIILECWQTDPNLRPSFA 915

  Fly  1455 TLLEHLTACTQDASIMNAPLPNILGPT 1481
            .|.|.|           .||..::.||
plant   916 QLTEVL-----------KPLNRLVLPT 931

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alk	NP_001261027.1	MAM	288..450	CDD:279023
		MAM	288..447	CDD:99706
		MAM	505..691	CDD:279023
		MAM	505..689	CDD:99706
		PTKc_ALK_LTK	1186..1462	CDD:270632	89/289 (31%)
		TyrKc	1193..1460	CDD:197581	84/269 (31%)
EDR1	NP_563824.1	EDR1	129..327	CDD:291079
		Pkinase_Tyr	669..921	CDD:285015	84/269 (31%)
		STKc_MAP3K-like	675..921	CDD:270901	83/263 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000