Protein Alignment Alk and drl

DIOPT Version :9

• Sequence 1: NP_001261027.1
• Gene: Alk / 53425
• FlyBaseID: FBgn0040505
• Length: 1701
• Species: Drosophila melanogaster
• Sequence 2: NP_001260566.1
• Gene: drl / 44355
• FlyBaseID: FBgn0015380
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 490
• Identity: 121/490 - (24%)
• Similarity: 209/490 - (42%)
• Gaps: 96/490 - (19%)

  Fly  1008 GGDVYLTESNGEG--GSSYISPSRSLREISE--IHAGASSG--------------PGAIIIIPAI 1054
            |||::..:.|.|.  .:.:.:|.:....::|  :..|.|.|              |.|..::..|
  Fly   183 GGDIHYVDRNDEHVVANGHQAPEKQRPVVTESPVGRGNSGGSKRDFDPMLRENLVPPASGLVTLI 247

  Fly  1055 EGCGCDYRCVALDEFRSKVR-CICPDGWSLKRDNHTACEIREEAGKSSFQYLVSILMISLAVLFI 1118
            .|     ..:||....:.:. ..|..|.|.:..::....|:    .||||.|.:|...:...:::
  Fly   248 VG-----GILALVLVSTLILIAYCAKGPSKRHPSNGVHLIK----TSSFQRLPTISSTAHNSIYV 303

  Fly  1119 CIA------ALIFMLYNRYQRKKQSKKRHKMLVEQDLQLTRLRNNIDDSNLNNFNPNYGCDGILN 1177
            |.:      |.:...:..|:.:.:...|.  |.|..:|..|:|
  Fly   304 CPSTITPTYATLTRPFREYEHEPEEFNRR--LQELTVQKCRVR---------------------- 344

  Fly  1178 GHIDVNSLPQVARDSLQLVNALGKGAFGEVYMALYRHRDGDAVEMGVAVKTLREDPKREKEEDFL 1242
                ::.|.|             :|.||.:|...|    .|..|  |.|||:.:...:.:....|
  Fly   345 ----LSCLVQ-------------EGNFGRIYRGTY----NDCQE--VLVKTVAQHASQLQVNLLL 386

  Fly  1243 KEAAIMAKFNHPNMVHLIGVCFDRQPYYIVLELLAGG--DLQKFLRENRNTPERPSLLTMKDLLF 1305
            :|:.::.:.:|||::.::|:..:......||....|.  :|:.||::    |.....:|....:.
  Fly   387 QESMMLYEASHPNVLSVLGISIEDYATPFVLYAATGSVRNLKSFLQD----PSYARSVTTIQTVL 447

  Fly  1306 CALDVAKGCRYMESKRFIHRDIAARNCLLSSKGPGRVVKIADFGMSRDIYRSDYYRKGGKAMLPI 1370
            ....:|....::.:...||:|||||||::..:   ..||:.|..:|||::..||...|.....||
  Fly   448 MGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQ---LRVKLTDSALSRDLFPGDYNSLGDGEYRPI 509

  Fly  1371 KWMPPEAFLDGIFTSKTDVWSFGILLWEVFSLGRSPYPGQHNTQVMELVVRGG-RLGSPTECPVS 1434
            ||:..||.....:...:||||||:|:||:.:||:.|| .:.:...||..::.| ||..|..||..
  Fly   510 KWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPY-AEIDPYEMEHYLKDGYRLAQPFNCPDE 573

  Fly  1435 IYKVMADCWNPTPEDRPTF----ITLLEHLTACTQ 1465
            ::.:||.||...|.:||:|    |.|.|..|..|:
  Fly   574 LFTIMAYCWASMPAERPSFSQLQICLSEFHTQITR 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alk	NP_001261027.1	MAM	288..450	CDD:279023
		MAM	288..447	CDD:99706
		MAM	505..691	CDD:279023
		MAM	505..689	CDD:99706
		PTKc_ALK_LTK	1186..1462	CDD:270632	83/282 (29%)
		TyrKc	1193..1460	CDD:197581	82/273 (30%)
drl	NP_001260566.1	WIF	21..157	CDD:128745
		PTK_Ryk	336..606	CDD:270639	88/322 (27%)
		Pkinase_Tyr	343..599	CDD:285015	83/308 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455369
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940