Protein Alignment Alk and Ror

DIOPT Version :10

• Sequence 1: NP_652600.1
• Gene: Alk / 53425
• FlyBaseID: FBgn0040505
• Length: 1701
• Species: Drosophila melanogaster
• Sequence 2: NP_476962.1
• Gene: Ror / 34367
• FlyBaseID: FBgn0010407
• Length: 685
• Species: Drosophila melanogaster
• Alignment Length: 472
• Identity: 150/472 - (31%)
• Similarity: 245/472 - (51%)
• Gaps: 71/472 - (15%)

  Fly  1019 EGGSSY-----ISPSRS--------LREISE----IHAGASSGPGAIIIIPAIEGCGCDYRCVAL 1066
            |.||:|     :|.|..        ::|||:    |.......||::...|   .|..|
  Fly   240 EDGSTYRGVANVSASGKPCLRWSWLMKEISDFPELIGQNYCRNPGSVENSP---WCFVD------ 295

  Fly  1067 DEFRSKVRCICPDGWSLKRDNHTACEIREEAGKSSFQYLVSILMISLAVLFICIAALIFMLYNRY 1131
               .|:.|.|            ..|:|.:.|.|    ..::|:..:.|::.|.|.....:|:
  Fly   296 ---SSRERII------------ELCDIPKCADK----IWIAIVGTTAAIILIFIIIFAIILF--- 338

  Fly  1132 QRKKQSKKRHKMLVEQDLQLTRLRNNI-DDSNLNNF-NPNYGCDGILNGHIDVNSLPQVARDSLQ 1194
              |:::...:.|....::.......|| .:|.|||. :...|..|.|:.|:.:|| ..:.|::|.
  Fly   339 --KRRTIMHYGMRNIHNINTPSADKNIYGNSQLNNAQDAGRGNLGNLSDHVALNS-KLIERNTLL 400

  Fly  1195 LVN-----------ALGKGAFGEVYMALYRHRDGDAVEMGVAVKTLREDPKREKEEDFLKEAAIM 1248
            .:|           .||:||||:||.......:...:.  ||:|.|:|:...:.::||.:|..::
  Fly   401 RINHFTLQDVEFLEELGEGAFGKVYKGQLLQPNKTTIT--VAIKALKENASVKTQQDFKREIELI 463

  Fly  1249 AKFNHPNMVHLIGVCFDRQPYYIVLELLAGGDLQKFLRENRNTPERPSLLTMKDLLFCALDVAKG 1313
            :...|.|:|.::||..:::||.::.|.:|.|||.:||..  |:|.....|:..:.|..||.:::|
  Fly   464 SDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLIS--NSPTEGKSLSQLEFLQIALQISEG 526

  Fly  1314 CRYMESKRFIHRDIAARNCLLSSKGPGRVVKIADFGMSRDIYRSDYYRKGGKAMLPIKWMPPEAF 1378
            .:|:.:..::|||:||||||::.   |.||||:|||:|||||.|||||...|::||::|||.|:.
  Fly   527 MQYLSAHHYVHRDLAARNCLVNE---GLVVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESI 588

  Fly  1379 LDGIFTSKTDVWSFGILLWEVFSLGRSPYPGQHNTQVMELVVRGGRLGSPTECPVSIYKVMADCW 1443
            |.|.||:::||||||::|||::|.|..||.|..|.:|:.|:.....|.:|..||.::|.:|.:||
  Fly   589 LYGKFTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECW 653

  Fly  1444 NPTPEDRPTFITLLEHL 1460
            :.....||||..:...|
  Fly   654 HEQSVKRPTFTDISNRL 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alk	NP_652600.1	MAM	288..447	CDD:99706
		MAM	505..689	CDD:99706
		PTKc_ALK_LTK	1186..1462	CDD:270632	109/286 (38%)
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568
		KR	235..312	CDD:214527	20/95 (21%)
		PTKc_Ror	404..673	CDD:270642	106/274 (39%)