Protein Alignment Alk and F09A5.2

DIOPT Version :9

• Sequence 1: NP_001261027.1
• Gene: Alk / 53425
• FlyBaseID: FBgn0040505
• Length: 1701
• Species: Drosophila melanogaster
• Sequence 2: NP_001360730.1
• Gene: F09A5.2 / 181440
• WormBaseID: WBGene00008599
• Length: 867
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 160/546 - (29%)
• Similarity: 240/546 - (43%)
• Gaps: 138/546 - (25%)

  Fly  1058 GCDYRCVALDEFRSKVRCICPDGWSLKRDNHTACEI-----REEAGKSSFQYLVSILMISLAVLF 1117
            ||.|       ..|:..|...| ||...:|....||     :....|..|.:.|:.|::.:.:..
 Worm   307 GCKY-------MNSRSYCEIVD-WSYHSENPNEFEICIPDSQPSGKKEDFNWHVTELLLIIGIPC 363

  Fly  1118 I-----CIAALIFMLYNRYQRKKQSKKRHKMLVEQDLQLTRLRNNI--DDSNLN----------- 1164
            |     |||..:..|       |.:|          |::..:|.|:  :|::.|
 Worm   364 ISLTICCIAFFVCCL-------KCAK----------LKMAMMRMNVFSNDTHQNPDEMELKKRWI 411

  Fly  1165 ----NFN---PNYGCDGI----------LNGHIDVNSLPQVAR------DSLQLV----NALGKG 1202
                .||   .|..|..:          .|.::|:.:|....:      |:..|:    :.||.|
 Worm   412 GMRKKFNKDVENGSCKELNTQKWSHFASANNYMDIQALANANKKDIWEIDTKNLLVQEDHLLGNG 476

  Fly  1203 AFGEVYMALYRHR-----DGDAVEMGV----------AVKTLREDPKREKEEDFLKEAAIMAKF- 1251
            ||..||..:.:.:     ..:::.|.|          |:|.|......:...||..|...|.:.
 Worm   477 AFANVYKGIVKGKIPLLVVNNSLNMTVESENNGHYEAAIKKLPAHADEQNHLDFFHEIDFMKRLG 541

  Fly  1252 NHPNMVHLIGVCFDRQPY--YIVLELLAGGDLQKFLRENRN------TPERP----SLLTMKDLL 1304
            :||:::.::| |.. .||  .||:|..|.|||.||||.:::      |.:.|    ..|.:|||:
 Worm   542 HHPHVISMLG-CVS-NPYEPLIVVEYCARGDLLKFLRRHKDYVLMNKTDDCPIEADMCLRIKDLV 604

  Fly  1305 FCALDVAKGCRYMESKRFIHRDIAARNCLLSSKGPGRVVKIADFGMSRDIYRSDYYRKGGKAMLP 1369
            ..|..||.|..|:.||.|||||:||||.||:.   ....|::|||:.|.:..:.|..|||:  ||
 Worm   605 SIAWQVADGMSYLASKNFIHRDLAARNILLTK---SLTAKVSDFGLCRYMDSALYTAKGGR--LP 664

  Fly  1370 IKWMPPEAFLDGIFTSKTDVWSFGILLWEVFSLGRSPYPGQHNTQVMELVVRGGRLGSPTECPVS 1434
            ||||..||.....|::||||||||:||:|:||:|..|||......::|.::.||||..|.:||..
 Worm   665 IKWMSVEALKLYEFSTKTDVWSFGVLLFEIFSMGDVPYPTIQQVDMLEHLLAGGRLSQPLKCPNE 729

  Fly  1435 IYKVMADCWNPTPEDRPTF------ITLLEHLTACTQDASIMNAPLPNILGPTASERDDTVIRPP 1493
            |:.:|..||...|||||.|      ||::.:|    .|.|.....:.:..||..::
 Worm   730 IFNIMQKCWAEKPEDRPEFNEMRGEITVMLNL----DDESYGYLSVESQGGPKYTQ--------- 781

  Fly  1494 NGEEFCLAVPDYLVPLP---PGGSNN 1516
                  |.:.|.....|   ||||.:
 Worm   782 ------LTMQDSKETAPCSTPGGSQD 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alk	NP_001261027.1	MAM	288..450	CDD:279023
		MAM	288..447	CDD:99706
		MAM	505..691	CDD:279023
		MAM	505..689	CDD:99706
		PTKc_ALK_LTK	1186..1462	CDD:270632	115/319 (36%)
		TyrKc	1193..1460	CDD:197581	113/304 (37%)
F09A5.2	NP_001360730.1	PTKc	473..752	CDD:270623	110/285 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910