Protein Alignment PLG and CG4914

DIOPT Version :10

• Sequence 1: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Sequence 2: NP_648711.1
• Gene: CG4914 / 39597
• FlyBaseID: FBgn0036436
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 98/263 - (37%)
• Similarity: 134/263 - (50%)
• Gaps: 32/263 - (12%)

Human   558 PQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAH 622
            |.|   |..||:...|     .|:|||.......:||...| :.|...:||||||:..:||||||
  Fly   113 PTC---SCRCGERNDE-----SRIVGGTTTGVSEYPWMARL-SYFNRFYCGGTLINDRYVLTAAH 168

Human   623 CLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTR-----KDIALLKLSSPAVITDKVI 682
            |: |.......||..|.|...|.:...:...|.|.|.:...     .|||||:|:....||..:.
  Fly   169 CV-KGFMWFMIKVTFGEHDRCNDKERPETRFVLRAFSQKFSFSNFDNDIALLRLNDRVPITSFIR 232

Human   683 PACLPSPNYVVADRTECFI------TGWG--ETQGTFGAGLLKEAQLPVIENKVC-NRYEFLNGR 738
            |.|||.    |..|.:.|:      ||||  :..|. .:.||:|.::||::|..| .:..:....
  Fly   233 PICLPR----VEQRQDLFVGTKAIATGWGTLKEDGK-PSCLLQEVEVPVLDNDECVAQTNYTQKM 292

Human   739 VQSTELCAGHL-AGGTDSCQGDSGGPLVCFEKD--KYILQGVTSWGLGCARPNKPGVYVRVSRFV 800
            :....:|:|:. .||.||||||||||||....|  ::...|:.|||.||||||.||||.||::::
  Fly   293 ITKNMMCSGYPGVGGRDSCQGDSGGPLVRLRPDDKRFEQIGIVSWGNGCARPNYPGVYTRVTKYL 357

Human   801 TWI 803
            .||
  Fly   358 DWI 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416
		KR	479..560	CDD:214527	1/1 (100%)
		Tryp_SPc	581..804	CDD:238113	91/240 (38%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	91/240 (38%)