Protein Alignment PLG and Ser8

DIOPT Version :10

• Sequence 1: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Sequence 2: NP_610874.1
• Gene: Ser8 / 36489
• FlyBaseID: FBgn0019928
• Length: 260
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 84/254 - (33%)
• Similarity: 118/254 - (46%)
• Gaps: 46/254 - (18%)

Human   572 VEPK--KCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYK 634
            :||:  ...||:|||..:.....||||||: |.|.|||||::||...::||||||:.....|:.:
  Fly    24 LEPQTSSLGGRIVGGTASSIEDRPWQVSLQ-RSGSHFCGGSIISNNIIVTAAHCLDTPTTVSNLR 87

Human   635 VILG-----------------AHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVI 682
            :..|                 ||:..|....:.:|.|.||          ..||:..:.|  |.|
  Fly    88 IRAGSNKRTYGGVLVEVAAIKAHEAYNSNSKINDIGVVRL----------KTKLTFGSTI--KAI 140

Human   683 PACLPSPNYVVADRTECFITGWGE--TQGTFGAGLLKEAQLPVIENKVCNRYEFLNGR-VQSTEL 744
            .....:|    |..:...|:|||:  |.|...|.|| .....::....|....:..|. :::|.:
  Fly   141 TMASATP----AHGSAASISGWGKTSTDGPSSATLL-FVDTRIVGRSQCGSSTYGYGSFIKATMI 200

Human   745 CAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWI 803
            ||.  |...|:||||||||||...:    |.||.|||..||..|.||||..::....|:
  Fly   201 CAA--ATNKDACQGDSGGPLVSGGQ----LVGVVSWGRDCAVANYPGVYANIAELRDWV 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416
		KR	479..560	CDD:214527
		Tryp_SPc	581..804	CDD:238113	80/243 (33%)
Ser8	NP_610874.1	Tryp_SPc	35..253	CDD:238113	79/241 (33%)