Protein Alignment PLG and Try29F

DIOPT Version :10

• Sequence 1: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Sequence 2: NP_523518.2
• Gene: Try29F / 34226
• FlyBaseID: FBgn0015316
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 250
• Identity: 94/250 - (37%)
• Similarity: 123/250 - (49%)
• Gaps: 33/250 - (13%)

Human   572 VEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSP------RP 630
            |...:..||:|||.||:....|:||||:..:  |||||:||:..||||||||.|.|.      |.
  Fly    33 VRRPRLDGRIVGGQVANIKDIPYQVSLQRSY--HFCGGSLIAQGWVLTAAHCTEGSAILLSKVRI 95

Human   631 SSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRK------DIALLKLS--SPAVITDKVIPACLP 687
            .|.:..:|.          |.:.:.|:...|...      |.:||:|.  |...:|...:.  ||
  Fly    96 GSSRTSVGG----------QLVGIKRVHRHPKFDAYTIDFDFSLLELEEYSAKNVTQAFVG--LP 148

Human   688 SPNYVVADRTECFITGWGETQGT-FGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAG 751
            ..:..:||.|...::|||.||.. ..:.:|:...:|.:....|.......|.:....||||...|
  Fly   149 EQDADIADGTPVLVSGWGNTQSAQETSAVLRSVTVPKVSQTQCTEAYGNFGSITDRMLCAGLPEG 213

Human   752 GTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGV 806
            |.|:|||||||||..    ..:|.||.|||.||||||.||||.|||....||..|
  Fly   214 GKDACQGDSGGPLAA----DGVLWGVVSWGYGCARPNYPGVYSRVSAVRDWISSV 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416
		KR	479..560	CDD:214527
		Tryp_SPc	581..804	CDD:238113	89/237 (38%)
Try29F	NP_523518.2	Tryp_SPc	42..264	CDD:238113	90/239 (38%)