Protein Alignment PLG and CG9673

DIOPT Version :10

• Sequence 1: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Sequence 2: NP_573149.1
• Gene: CG9673 / 32649
• FlyBaseID: FBgn0030775
• Length: 261
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 70/247 - (28%)
• Similarity: 110/247 - (44%)
• Gaps: 37/247 - (14%)

Human   579 GRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEK---SP-RPSSYKVILGA 639
            ||::||.......:||..|:|.. ..|.|.|.:||...:||||||:..   :| ..|:..|.||.
  Fly    27 GRILGGEDVAQGEYPWSASVRYN-KAHVCSGAIISTNHILTAAHCVSSVGITPVDASTLAVRLGT 90

Human   640 HQEVNLEPHVQEIEVSRLFLEPT----RKDIALLKLSSPAVITDKVIPACLPS------------ 688
               :|.......:.|..:.:.|:    ..|||:|:|....|.:|::....||.
  Fly    91 ---INQYAGGSIVNVKSVIIHPSYGNFLHDIAILELDETLVFSDRIQDIALPPTTDEETEDVDAE 152

Human   689 -PNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGG 752
             ||     .|..::.||||......:...::|....:...:|   |:..|....:.:|... |.|
  Fly   153 LPN-----GTPVYVAGWGELSDGTASYKQQKANYNTLSRSLC---EWEAGYGYESVVCLSR-AEG 208

Human   753 TDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIE 804
            ...|:||:|..::  :.|| :|:|:||:..|......|.|..|||.::||||
  Fly   209 EGICRGDAGAAVI--DDDK-VLRGLTSFNFGPCGSKYPDVATRVSYYLTWIE 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416
		KR	479..560	CDD:214527
		Tryp_SPc	581..804	CDD:238113	66/243 (27%)
CG9673	NP_573149.1	Tryp_SPc	28..256	CDD:214473	66/243 (27%)