Protein Alignment PLG and CG6048

DIOPT Version :10

• Sequence 1: NP_000292.1
• Gene: PLG / 5340
• HGNCID: 9071
• Length: 810
• Species: Homo sapiens
• Sequence 2: NP_572282.1
• Gene: CG6048 / 31528
• FlyBaseID: FBgn0029827
• Length: 362
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 87/263 - (33%)
• Similarity: 123/263 - (46%)
• Gaps: 44/263 - (16%)

Human   578 PGRVVGGCVAHPHSWPWQVSLRTR------FGM-HFCGGTLISPEWVLTAAHCLEKS-------- 627
            |||::.|..|...:...||.:|..      ||. |.|||:||.|.||||||||....
  Fly    43 PGRIINGTEASLGATRHQVGIRKALNDGYFFGTGHLCGGSLIRPGWVLTAAHCFVDQIIYDGTFV 107

Human   628 PRPSSYKVILGAHQEVN--------LEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPA 684
            |: ..:.|::|.....|        :|..:.:::  :..|....||||||.|:.       .:|.
  Fly   108 PK-EEFIVVMGNLDRYNRTNTLTFTIEERIMQLD--KFDLSTYDKDIALLMLNG-------TVPT 162

Human   685 CLPS------PNYVVADRTECFITGWGETQGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTE 743
            ..|:      ..:.:.:...|.:||||.|:..:.:.:|....:|:|..:.|.....|...:|...
  Fly   163 GHPTIRPIALNRFAIPEGVVCQVTGWGNTEDGYVSDILMTVDVPMISEEHCINDSDLGHLIQPGM 227

Human   744 LCAGHL-AGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 807
            :|||:| .|..|:|.|||||||||..:    |.||.|||:.||.|..||||..||.:..||...|
  Fly   228 ICAGYLEVGEKDACAGDSGGPLVCQSE----LAGVVSWGIQCALPRLPGVYTEVSYYYDWILQNM 288

Human   808 RNN 810
            ..|
  Fly   289 GEN 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLG	NP_000292.1	PAN_AP_HGF	<38..97	CDD:238532
		KR	101..183	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..145
		KR	183..263	CDD:214527
		KR	273..354	CDD:214527
		KR	375..456	CDD:214527
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	396..416
		KR	479..560	CDD:214527
		Tryp_SPc	581..804	CDD:238113	81/252 (32%)
CG6048	NP_572282.1	Tryp_SPc	45..284	CDD:214473	81/252 (32%)