Protein Alignment PLD2 and Pld2

DIOPT Version :10

• Sequence 1: NP_002654.3
• Gene: PLD2 / 5338
• HGNCID: 9068
• Length: 933
• Species: Homo sapiens
• Sequence 2: XP_038941178.1
• Gene: Pld2 / 25097
• RGDID: 3350
• Length: 972
• Species: Rattus norvegicus
• Alignment Length: 972
• Identity: 844/972 - (86%)
• Similarity: 875/972 - (90%)
• Gaps: 39/972 - (4%)

Human     1 MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFAPGVPV 65
            ||.|...|||.||.|:||||.||.|||||||||||||||||||||||:||.|:.|||||||||||
  Rat     1 MTVTQTDLFPYGDYLNSSQLHMEPDEVDTLKEGEDPADRMHPFLAIYDLQPLRAHPLVFAPGVPV 65

Human    66 TAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSLLPLARFA 130
            .||||||||||||||||||||||||||||||:||||||:||||||||||.|||||||||||||||
  Rat    66 IAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLQRHKVLMSLLPLARFA 130

Human   131 VAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLS 195
            .|:||||:|.|..:|||||.|.|||.||.||||||||||||||||||||||||||||||||||||
  Rat   131 AAHSPAREAANENIPSLPRGGSEGSARHTASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLS 195

Human   196 FIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQL 260
            ||||||.|||||:||||||||||||.|||||||||||||||||||||||||||..||||||||||
  Rat   196 FIPDLGSKGLEGVIRKRSGGHRVPGFTCCGRDQVCYRWSKRWLVVKDSFLLYMRPETGAISFVQL 260

Human   261 FDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDS 325
            |||||||||||||||||:||||||||||||||||||||||||.||||||||||||||||||:|||
  Rat   261 FDPGFEVQVGKRSTEARYGVRIDTSHRSLILKCSSYRQARWWGQEITELAQGPGRDFLQLHQHDS 325

Human   326 YAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRK 390
            ||||||||||||||||||||||||||||||:|||||||||||||:||||||||||||||||||||
  Rat   326 YAPPRPGTLARWFVNGAGYFAAVADAILRAREEIFITDWWLSPEIYLKRPAHSDDWRLDIMLKRK 390

Human   391 AEEGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFL 455
            ||||||||||||||||||||||||||||.|||||||||||||||.|||||||||||||||.||||
  Rat   391 AEEGVRVSILLFKEVELALGINSGYSKRTLMLLHPNIKVMRHPDLVTLWAHHEKLLVVDQAVAFL 455

Human   456 GGLDLAYGRWDDLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWV 520
            ||||||||||||:.||||||||.||||.||.|||..|..||||||||.|||||||||||||||||
  Rat   456 GGLDLAYGRWDDVQYRLTDLGDPSESADSQTPTPGSDPAATPDLSHNHFFWLGKDYSNLITKDWV 520

Human   521 QLDRPFE---------------------------------------DFIDRETTPRMPWRDVGVV 546
            |||||||                                       |||||||||||||||||||
  Rat   521 QLDRPFEEEVRTGTQPEQEPGGLLLPGSFPVDSSVSFLPEPRTTTPDFIDRETTPRMPWRDVGVV 585

Human   547 VHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQCTTVQVLRSVD 611
            |||:.|||||||||||||||||.||:||.|.||||||||.||||.|||.:||.||.|||||||||
  Rat   586 VHGVAARDLARHFIQRWNFTKTIKARYKIPQYPYLLPKSASTANHLPFIIPGAQCATVQVLRSVD 650

Human   612 RWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYR 676
            ||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||:||.|:|
  Rat   651 RWSAGTLESSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHEQGQCFR 715

Human   677 VYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTH 741
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||
  Rat   716 VYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYMSICGLRTH 780

Human   742 GELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEY 806
            |||||||:|||||||||:|||||||||||||||||||||||||||||:||||||.|||||:|.||
  Rat   781 GELGGHPISELIYIHSKLLIADDRTVIIGSANINDRSLLGKRDSELAILIEDTEMEPSLMDGVEY 845

Human   807 QAGRFALSLRKHCFGVILGANTRPDLDLRDPICDDFFQLWQDMAESNANIYEQIFRCLPSNATRS 871
            ||||||||||||||.|||||||.||||||||:|||||||||:.||:||.||||||||||||||||
  Rat   846 QAGRFALSLRKHCFSVILGANTWPDLDLRDPVCDDFFQLWQETAENNATIYEQIFRCLPSNATRS 910

Human   872 LRTLREYVAVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT 933
            ||.||||||||.||||||.||:|||..::|||||||||||||||||||||||||||||||||
  Rat   911 LRALREYVAVESLATVSPSLAQSELAHIRGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT 972

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLD2	NP_002654.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		23/32 (72%)
		PLN02866	66..918	CDD:215467	775/890 (87%)
		Catalytic	441..788		316/385 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	477..497		12/19 (63%)
Pld2	XP_038941178.1	PLN02866	67..957	CDD:215467	775/889 (87%)