Protein Alignment PLD2 and Pld2

DIOPT Version :10

• Sequence 1: NP_002654.3
• Gene: PLD2 / 5338
• HGNCID: 9068
• Length: 933
• Species: Homo sapiens
• Sequence 2: NP_001289404.1
• Gene: Pld2 / 18806
• MGIID: 892877
• Length: 944
• Species: Mus musculus
• Alignment Length: 944
• Identity: 840/944 - (88%)
• Similarity: 876/944 - (92%)
• Gaps: 11/944 - (1%)

Human     1 MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFAPGVPV 65
            ||.|.::|||.||.|:||||.||.||||||:|||||||||||:||||:||.||.|||||||||||
Mouse     1 MTVTQKNLFPYGDYLNSSQLHMEPDEVDTLREGEDPADRMHPYLAIYDLQPLKAHPLVFAPGVPV 65

Human    66 TAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSLLPLARFA 130
            .||||||||||||||||||||||||||||||:||||||:||||||||||.|||||||||||||||
Mouse    66 IAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLQRHKVLMSLLPLARFA 130

Human   131 VAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLS 195
            |.:||||:|...::|||||.|.|||.||.||||||||||||||||||||||||||||||||||||
Mouse   131 VTHSPAREAAAEDIPSLPRGGSEGSARHTASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLS 195

Human   196 FIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQL 260
            ||||||.|||||:||||||||||||.|.|||||||||||||||||||||||||..||||||||||
Mouse   196 FIPDLGSKGLEGVIRKRSGGHRVPGFTFCGRDQVCYRWSKRWLVVKDSFLLYMRPETGAISFVQL 260

Human   261 FDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDS 325
            |||||||||||||||.|:||||||||||||||||||||||||.|||||||||.||||||||:|||
Mouse   261 FDPGFEVQVGKRSTETRYGVRIDTSHRSLILKCSSYRQARWWGQEITELAQGSGRDFLQLHQHDS 325

Human   326 YAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRK 390
            ||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||
Mouse   326 YAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEIYLKRPAHSDDWRLDIMLKRK 390

Human   391 AEEGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFL 455
            ||||||||||||||||||||||||||||.|||||||||||||||.||||||||||||||||||||
Mouse   391 AEEGVRVSILLFKEVELALGINSGYSKRTLMLLHPNIKVMRHPDLVTLWAHHEKLLVVDQVVAFL 455

Human   456 GGLDLAYGRWDDLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWV 520
            ||||||:|||||:.||||||||.||....|.||...|..||||||||||||||||||||||||||
Mouse   456 GGLDLAFGRWDDVQYRLTDLGDPSEPVHLQTPTLGSDPAATPDLSHNQFFWLGKDYSNLITKDWV 520

Human   521 QLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKS 585
            |||||||||||||||||||||||||||||:.||||||||||||||||||||:||||.||||||||
Mouse   521 QLDRPFEDFIDRETTPRMPWRDVGVVVHGVAARDLARHFIQRWNFTKTTKARYKTPLYPYLLPKS 585

Human   586 TSTANQLPFTLPGGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDG 650
            |||||.|||.:|||||.||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   586 TSTANNLPFMIPGGQCATVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDG 650

Human   651 RTVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTY-------- 707
            |||||||||||||||||||:||.|:|||:||||||||||||||||||||||||||||
Mouse   651 RTVLNKVGDEIVDRILKAHEQGQCFRVYLLLPLLPGFEGDISTGGGNSIQAILHFTYSLCLLHPF 715

Human   708 ---RTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVII 769
               |||||||:|||||||||||||||||:|||||||||||||||:|||||||||:||||||||||
Mouse   716 FSLRTLCRGEHSILHRLKAAMGTAWRDYMSICGLRTHGELGGHPISELIYIHSKMLIADDRTVII 780

Human   770 GSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDL 834
            |||||||||||||||||||:||:|||.|||||:|.||||||||||||||||.|||||||.|||||
Mouse   781 GSANINDRSLLGKRDSELAILIKDTEMEPSLMDGVEYQAGRFALSLRKHCFSVILGANTWPDLDL 845

Human   835 RDPICDDFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQV 899
            |||:|||||||||:.||:||.||||||||||||||||||.||||||||.||||||.||:|||..:
Mouse   846 RDPVCDDFFQLWQETAENNATIYEQIFRCLPSNATRSLRALREYVAVESLATVSPSLAQSELAHI 910

Human   900 QGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT 933
            ||||||||||||||||||||||||||||||||||
Mouse   911 QGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT 944

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLD2	NP_002654.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		22/32 (69%)
		PLN02866	66..918	CDD:215467	772/862 (90%)
		Catalytic	441..788		316/357 (89%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	477..497		8/19 (42%)
Pld2	NP_001289404.1	PLN02866	67..929	CDD:215467	772/861 (90%)