DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZFYVE1 and CG15602

DIOPT Version :9

Sequence 1:NP_067083.1 Gene:ZFYVE1 / 53349 HGNCID:13180 Length:777 Species:Homo sapiens
Sequence 2:NP_001285298.1 Gene:CG15602 / 32533 FlyBaseID:FBgn0030694 Length:342 Species:Drosophila melanogaster


Alignment Length:71 Identity:22/71 - (30%)
Similarity:31/71 - (43%) Gaps:6/71 - (8%)


- Green bases have known domain annotations that are detailed below.


Human   602 LSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTE 666
            :||..|...:.....::.|..||..||..|..:..||| |..|... .||..||:    :|:..:
  Fly     1 MSCFGCGRKYGLFCKEYGCPNCGYSFCSKCLKRPMPVP-RHAGKVH-NVCLICYD----KLSKLQ 59

Human   667 AQVDDE 672
            |..|.|
  Fly    60 ASADAE 65

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZFYVE1NP_067083.1 GBP 174..410 CDD:206650
Required for localization in the lipid droplets. /evidence=ECO:0000269|PubMed:30970241, ECO:0000269|PubMed:31293035 416..777 22/71 (31%)
FYVE_like_SF 594..655 CDD:333710 16/52 (31%)
FYVE_ZFYV1 711..771 CDD:277273
CG15602NP_001285298.1 PHD_SF 2..52 CDD:304600 16/51 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1818
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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