DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ATP6V0B and Vha16-2

DIOPT Version :9

Sequence 1:	NP_001281262.1	Gene:	ATP6V0B / 533	HGNCID:	861	Length:	261	Species:	Homo sapiens
Sequence 2:	NP_729707.1	Gene:	Vha16-2 / 39282	FlyBaseID:	FBgn0028668	Length:	158	Species:	Drosophila melanogaster

Alignment Length:	159	Identity:	48/159 - (30%)
Similarity:	84/159 - (52%)	Gaps:	20/159 - (12%)

- Green bases have known domain annotations that are detailed below.

Human    38 AWFLTETSPFMWSNLGIGLAISLSVVGAAWGIYITGSSIIGGGVKAPRIKTKNLVSIIFCEAVAI 102
            |:||..|        |..:||..:.:||::|..::|..|....|..|.:..|.::.::....:||
  Fly    13 AFFLGCT--------GAAVAIIFTTLGASYGTAVSGVGIAKMAVNRPDMIMKAIIPVVMAGIIAI 69

Human   103 YGIIMAIVIS-NMAEPFSATDPKAIGHRNYHAGYSMFGAGLTVGLSNLFCGVCVGIVGSGAALAD 166
            ||::::::|: ::.:.::..|           .|...||||:|||..|..||.:||.|.......
  Fly    70 YGLVVSVLIAGSIGDDYTMED-----------SYVHLGAGLSVGLPGLTAGVAIGIAGDAGVRGT 123

Human   167 AQNPSLFVKILIVEIFGSAIGLFGVIVAI 195
            |:.|.|||.::::.||...:.|:|:||||
  Fly   124 AEQPRLFVGMVLILIFAEVLALYGLIVAI 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V0B	NP_001281262.1	PRK08344	48..199	CDD:236246	44/149 (30%)
		ATP-synt_C	52..112	CDD:278563	15/59 (25%)
		ATP-synt_C	136..196	CDD:278563	26/60 (43%)
Vha16-2	NP_729707.1	PRK06558	14..158	CDD:235830	47/158 (30%)
		ATP-synt_C	15..120	CDD:294318	34/123 (28%)
		ATP-synt_C	94..154	CDD:278563	26/59 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810