Protein Alignment PLAU and CG11836

DIOPT Version :9

• Sequence 1: NP_002649.2
• Gene: PLAU / 5328
• HGNCID: 9052
• Length: 431
• Species: Homo sapiens
• Sequence 2: NP_001356925.1
• Gene: CG11836 / 43007
• FlyBaseID: FBgn0039272
• Length: 333
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 92/260 - (35%)
• Similarity: 140/260 - (53%)
• Gaps: 27/260 - (10%)

Human   168 CGQKTLRPRFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKK 232
            ||..  ....:|:||:.|.:...||.|.|....:     :.|||||::..:|:||.||.....|.
  Fly    88 CGFS--NEEIRIVGGKPTGVNQYPWMARIVYDGK-----FHCGGSLLTKDYVLSAAHCVKKLRKS 145

Human   233 EDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQP---SRT 294
            :..:::....:..::....::..|..:|.||.:..||  ::||||||::|       :|   |:.
  Fly   146 KIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDT--YNNDIALLRLR-------KPISFSKI 201

Human   295 IQTICLPSMYNDP--QFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTT 357
            |:.||||....||  :.||   :.|:|:.:....| |..:....|.::|..||:...|..:.:|:
  Fly   202 IKPICLPRYNYDPAGRIGT---VVGWGRTSEGGEL-PSIVNQVKVPIMSITECRNQRYKSTRITS 262

Human   358 KMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSH 422
            .||||..|  ..|||||||||||:.|...:..:.||||||.||..:..||||:|||.|:|||:|:
  Fly   263 SMLCAGRP--SMDSCQGDSGGPLLLSNGVKYFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSN 325

Human   423  422
              Fly   326  325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLAU	NP_002649.2	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	34..57
		KR	67..152	CDD:238056
		Connecting peptide	152..177		2/8 (25%)
		Tryp_SPc	179..422	CDD:238113	89/247 (36%)
CG11836	NP_001356925.1	Tryp_SPc	97..325	CDD:238113	89/247 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910