Protein Alignment PLAU and CG7432

DIOPT Version :9

• Sequence 1: NP_002649.2
• Gene: PLAU / 5328
• HGNCID: 9052
• Length: 431
• Species: Homo sapiens
• Sequence 2: NP_650825.2
• Gene: CG7432 / 42347
• FlyBaseID: FBgn0038727
• Length: 721
• Species: Drosophila melanogaster
• Alignment Length: 438
• Identity: 103/438 - (23%)
• Similarity: 160/438 - (36%)
• Gaps: 139/438 - (31%)

Human    98 TVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR--------------------------------- 129
            |.|.|.  |..||....|....|||:.|..||
  Fly   313 TPLDQL--AEASDEAGTGKDVENYCKTPSGRRGRCEDLSSCPALLLNLSSLRESLCFKSLYVPGV 375

Human   130 -----------------------------------------RPWCYVQVGLKLLVQECMVHDCAD 153
                                                     ||......||.|:.|
  Fly   376 CCPISSSSTVLTTQKPLRLTTRPTTTTSTTKATQPTKKSTVRPTTRPTSGLVLIPQ--------- 431

Human   154 GKKPSS-----------PPEEL---------KFQCGQKTLRPRFKIIGGEFTTIENQPWFAAIYR 198
             |||.:           .||.|         ..:|||:..... :|:||........||.|||:
  Fly   432 -KKPPTTTTTTTTEVPLEPEGLDEIGNNIVDPDECGQQEYSTG-RIVGGVEAPNGQWPWMAAIF- 493

Human   199 RHRGGSVTYVCGGSLISPCWVISATHCFIDYPKK----EDYIVYLGRSRLNSNTQ--GEMKFEVE 257
            .|......:.||||||...::::|.||..|..:|    ..:.|.||...|:::.:  ..:.|.|:
  Fly   494 LHGPKRTEFWCGGSLIGTKYILTAAHCTRDSRQKPFAARQFTVRLGDIDLSTDAEPSDPVTFAVK 558

Human   258 NLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQF----GTSCEITGF 318
            .:..|:.:|  .:..:||||:|.:    .:..:.|:.:..:|||.....|..    |....:.|:
  Fly   559 EVRTHERFS--RIGFYNDIAILVL----DKPVRKSKYVIPVCLPKGIRMPPKERLPGRRATVVGW 617

Human   319 ------GKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSG 377
                  |||:::.    .|.::.:.:   :.:|.:.::  ..:....:||.......|:||||||
  Fly   618 GTTYYGGKESTSQ----RQAELPIWR---NEDCDRSYF--QPINENFICAGYSDGGVDACQGDSG 673

Human   378 GPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTKE 425
            |||:..........|:||:|..|.....|||||||:.:|.|||.||::
  Fly   674 GPLMMRYDSHWVQLGVVSFGNKCGEPGYPGVYTRVTEYLDWIRDHTRD 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLAU	NP_002649.2	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	34..57
		KR	67..152	CDD:238056	19/127 (15%)
		Connecting peptide	152..177		9/44 (20%)
		Tryp_SPc	179..422	CDD:238113	73/258 (28%)
CG7432	NP_650825.2	CLIP	335..378	CDD:197829	4/42 (10%)
		Tryp_SPc	474..715	CDD:214473	70/256 (27%)
		Tryp_SPc	475..718	CDD:238113	73/258 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910