Protein Alignment PLAU and CG4998

DIOPT Version :9

• Sequence 1: NP_002649.2
• Gene: PLAU / 5328
• HGNCID: 9052
• Length: 431
• Species: Homo sapiens
• Sequence 2: NP_001036609.1
• Gene: CG4998 / 39808
• FlyBaseID: FBgn0036612
• Length: 1185
• Species: Drosophila melanogaster
• Alignment Length: 427
• Identity: 124/427 - (29%)
• Similarity: 189/427 - (44%)
• Gaps: 85/427 - (19%)

Human    45 FSNIHWCNCPKKFGG-----QHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTY 104
            |::|:..:.| .|||     ||  :::|.....|:         ||.      |.||
  Fly   794 FNSIYPGSSP-DFGGYGEYSQH--VERSANVSGGD---------TDR------PSNS-------- 832

Human   105 HAHRSDALQLG-------------LGKHNYCRNPDNRRRP-----WC-------YVQVGLKLLVQ 144
             ..|...|.||             .|........|.|||.     |.       ....|.:.:.:
  Fly   833 -GRRGKQLNLGPLYNIPTPAPGEAAGSDRITFPRDRRRRSVEDGVWAGAAPKEQRAYYGNRPVEK 896

Human   145 ECMVHD--CADGKKPSSPPEELKFQCGQKT---LRPRFK---IIGGEFTTIENQPWFAAIYRRHR 201
            .|.:::  |....:|.:||::.. :||.:.   :..|.|   .:.|: :.....||..||.::..
  Fly   897 TCRINEVCCRRPLRPQAPPQQFG-RCGVRNAAGITGRIKNPVYVDGD-SEFGEYPWHVAILKKDP 959

Human   202 GGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQ--GEMKFEVENLILHKD 264
            ..|: |.|||:||....:|||.|| |......|..|.||...:|.:.:  ..::.:|.::.:|.:
  Fly   960 KESI-YACGGTLIDAQHIISAAHC-IKSQNGFDLRVRLGEWDVNHDVEFFPYIERDVVSVHIHPE 1022

Human   265 YSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQF-GTSCEITGFGKENSTDY-L 327
            |.|.||  .||:|:||:.........|.  |...|||..|:|  | |..|..||:||:...:: .
  Fly  1023 YYAGTL--DNDLAVLKLDQPVDFTKNPH--ISPACLPDKYSD--FTGARCWTTGWGKDAFGEHGK 1081

Human   328 YPEQLKMTVVKLISHRECQQPHY-----YGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGR 387
            |...||...|.::||::|:....     |..::....:||...:.| |:|:||.||||||...|.
  Fly  1082 YQNILKEVDVPILSHQQCESQLRNTRLGYSYKLNPGFVCAGGEEGK-DACKGDGGGPLVCDRNGA 1145

Human   388 MTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK 424
            |.:.|:||||.||...:.||||.:||.:||||:..|:
  Fly  1146 MHVVGVVSWGIGCGQVNVPGVYVKVSAYLPWIQQITQ 1182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLAU	NP_002649.2	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	34..57		3/11 (27%)
		KR	67..152	CDD:238056	19/111 (17%)
		Connecting peptide	152..177		5/27 (19%)
		Tryp_SPc	179..422	CDD:238113	88/251 (35%)
CG4998	NP_001036609.1	Tryp_SPc	942..1180	CDD:238113	87/247 (35%)
		Tryp_SPc	942..1177	CDD:214473	85/244 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910