Protein Alignment PLAU and CG3700

DIOPT Version :9

• Sequence 1: NP_002649.2
• Gene: PLAU / 5328
• HGNCID: 9052
• Length: 431
• Species: Homo sapiens
• Sequence 2: NP_611736.1
• Gene: CG3700 / 37640
• FlyBaseID: FBgn0034796
• Length: 360
• Species: Drosophila melanogaster
• Alignment Length: 444
• Identity: 109/444 - (24%)
• Similarity: 170/444 - (38%)
• Gaps: 125/444 - (28%)

Human     7 RLLLCVLVVSDSKGSNELHQVPSNCDCLNG-GTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTC 70
            ::||.:..||         .|...||  || |.|      ..:...:||..|..||....:.|.|
  Fly     8 QILLLIASVS---------VVTEYCD--NGTGEC------KELTPSDCPVIFYNQHLIGAEVKYC 55

Human    71 YEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYV 135
            .|.|          |.:   |.|                    :.|...|.  .|..:.||:
  Fly    56 DEFN----------DIV---CCP--------------------IPLDHQNL--KPAEQTRPF--- 82

Human   136 QVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFAAI--YR 198
                   .::|..::            |::..|.....     |:||...:.:..|:.|.|  :|
  Fly    83 -------EKQCKQYN------------EVRSACQSTPF-----IVGGTKASGKEFPFMALIGTHR 123

Human   199 RHRGGS-VTYVCGGSLISPCWVISATHCF-------------IDYPKKEDYIVYLGRSRLNSNTQ 249
            .::..| :.:.||||::.|.:|::|.||.             .|.||   ::|.||....||.|.
  Fly   124 PNKSKSDINWDCGGSVVHPKFVLTAAHCLETDESKAERLDPNFDSPK---FVVRLGELDYNSTTD 185

Human   250 GEM--KFEVENLILHKDYSA--DTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL-PSMYNDPQF 309
            ..:  .|.|.|.::|..|..  :.....|||||:::..|    |:.:..:..:|| |...||.|
  Fly   186 DALVQDFRVVNYVVHPGYDTEDEEQGFKNDIALVELDRK----AEFNDHVAAVCLPPDSGNDVQ- 245

Human   310 GTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQG 374
                ::|..|...:.|.:....|....::..|...||:...:..:..|: .||.....:.|:|.|
  Fly   246 ----QVTAAGWGFTADGVKSSHLLKVNLQRFSDEVCQKRLRFSIDTRTQ-FCAGSMSSQADTCNG 305

Human   375 DSGGPLV-------CSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRS 421
            |||||:.       |..|    :.||||:|..|..:..|.|||:|..:..||.|
  Fly   306 DSGGPIFVQHPLYPCLKQ----VIGIVSYGLVCGSQGLPSVYTKVHLYTDWIES 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLAU	NP_002649.2	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	34..57		6/23 (26%)
		KR	67..152	CDD:238056	13/84 (15%)
		Connecting peptide	152..177		2/24 (8%)
		Tryp_SPc	179..422	CDD:238113	78/271 (29%)
CG3700	NP_611736.1	Tryp_SPc	102..356	CDD:238113	78/271 (29%)
		Tryp_SPc	102..353	CDD:214473	75/267 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910