Protein Alignment PLAU and CG4927

DIOPT Version :9

• Sequence 1: NP_002649.2
• Gene: PLAU / 5328
• HGNCID: 9052
• Length: 431
• Species: Homo sapiens
• Sequence 2: NP_001033953.1
• Gene: CG4927 / 36852
• FlyBaseID: FBgn0034139
• Length: 362
• Species: Drosophila melanogaster
• Alignment Length: 444
• Identity: 105/444 - (23%)
• Similarity: 167/444 - (37%)
• Gaps: 110/444 - (24%)

Human     1 MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNG-GTCVSNKYFSNIHWCNCPKKFGGQHCEI 64
            |:.:...||:..::.|         .:...||  || |.|      ..:...:||..|...|...
  Fly     1 MQVIFGILLILAVICS---------ILSEFCD--NGTGEC------KELSATDCPSIFFNLHLIR 48

Human    65 DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRR 129
            :..|.|.:.| |..           .||..|:.....|.:.|:
  Fly    49 NFVKYCDKSN-HIV-----------CCLLPNNMQPQSQQFSAN---------------------- 79

Human   130 RPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKIIGGEFTTIENQPWFA 194
                   :||:...:||...:            |::..|     |....|:||........|:.|
  Fly    80 -------IGLRRFEKECRRFN------------EIRTSC-----RTTPFIVGGAKAAGREFPFMA 120

Human   195 AIYRRHRGGS-VTYVCGGSLISPCWVISATHCFIDYPKKED----------YIVYLGRSRLNSNT 248
            .:.:|.:..| :.:.||..:|.|.:|::|.||......||.          |:|.||....||.|
  Fly   121 LLGQRGKNSSQIDWDCGAIIIHPKFVLTAAHCLETSETKEQRLDPNYDGPKYVVRLGELDYNSTT 185

Human   249 QG--EMKFEVENLILHKDYSA--DTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQF 309
            ..  ...|.|.|.::|..|..  ||.:..||||::::..:    |..|..:...|||....:.|.
  Fly   186 DDAQPQDFRVLNYVVHPAYGEDDDTGSRKNDIAVVELEME----ATFSEYVAPACLPLDGGNEQL 246

Human   310 GTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQG 374
            ..:.  .|:|..:.:.:.....||:::.: ....||.|...:..:|.|: |||.......|:|.|
  Fly   247 QVAA--AGWGATSESGHASSHLLKVSLDR-YDVAECSQRLEHKIDVRTQ-LCAGSRSTSADTCYG 307

Human   375 DSGGPLV-------CSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRS 421
            |||||:.       |..|    :.||.|:|..|.::..|.|||:|..:..||.:
  Fly   308 DSGGPVFVQHPIYSCLKQ----VIGITSYGLVCGVQGLPSVYTKVHLYTDWIEN 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLAU	NP_002649.2	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	34..57		6/23 (26%)
		KR	67..152	CDD:238056	13/84 (15%)
		Connecting peptide	152..177		3/24 (13%)
		Tryp_SPc	179..422	CDD:238113	75/265 (28%)
CG4927	NP_001033953.1	Tryp_SPc	105..358	CDD:238113	75/265 (28%)
		Tryp_SPc	105..355	CDD:214473	73/261 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910