Protein Alignment PLAU and CG5390

DIOPT Version :9

• Sequence 1: NP_002649.2
• Gene: PLAU / 5328
• HGNCID: 9052
• Length: 431
• Species: Homo sapiens
• Sequence 2: NP_001285802.1
• Gene: CG5390 / 34383
• FlyBaseID: FBgn0032213
• Length: 406
• Species: Drosophila melanogaster
• Alignment Length: 440
• Identity: 115/440 - (26%)
• Similarity: 171/440 - (38%)
• Gaps: 120/440 - (27%)

Human    51 CNCPKKFGGQHCEIDK-----------------------SKTCYEGNGHFYRGKASTDTMG---- 88
            |.|....|.|...:||                       .|......|....|.:||....
  Fly    10 CLCIFSCGAQDSSLDKLISDIFKTDETPKPSSPPPPVVNPKDSSGSTGSENGGSSSTQYQSCGDQ 74

Human    89 RPCLP-WNSATVLQQTYHAHRSDALQLGLGKHNYCRN--------PDNRRRPWCYVQVGLKLLVQ 144
            :.|:| |..|   ..|.:......:.:.||....|:|        |:.|:.|           :.
  Fly    75 KECVPRWLCA---NDTINTSGDGIIDIRLGTDAECKNYLDLCCDLPNKRKDP-----------IF 125

Human   145 ECMVHDCADGKKPSSPPEELKFQCGQKTLRPR---FKIIG--------GEFTTIENQPWFAAIYR 198
            |.         ||..|.     .||.:  .|.   |||.|        |||      ||..||.
  Fly   126 EF---------KPDHPE-----GCGYQ--NPNGVGFKITGAVNQEAEFGEF------PWMLAIL- 167

Human   199 RHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFE----VENL 259
            |..|....|.|||:||:|..|::|.||   ...|:...:.:.....::.||.|::..    |:.:
  Fly   168 REEGNLNLYECGGALIAPNVVLTAAHC---VHNKQPSSIVVRAGEWDTQTQTEIRRHEDRYVKEI 229

Human   260 ILHKDYSADTLAHHNDIALLKIRSKEGRCAQP---SRTIQTICLPSMYNDPQFGTSCEITGFGKE 321
            |.|:.::..:|  :||:|::.:.|       |   ...|||:|||::.:...| ..|..||:||.
  Fly   230 IYHEQFNKGSL--YNDVAVMLLES-------PFTLQENIQTVCLPNVGDKFDF-DRCYATGWGKN 284

Human   322 N-STDYLYPEQLKMTVVKLISHRECQQ--------PHYYGSEVTTKMLCAADPQWKTDSCQGDSG 377
            . ..|..|...||...:.::..::|:.        .|:.   :....:||...:.| |:|:||.|
  Fly   285 KFGKDGEYQVILKKVDMPVVPEQQCETNLRETRLGRHFI---LHDSFICAGGEKDK-DTCKGDGG 345

Human   378 GPLVCSLQG---RMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK 424
            .||||.:.|   |....|||:||.||...:.||||..|:...|||.:..|
  Fly   346 SPLVCPIAGQKNRFKSAGIVAWGIGCGEVNIPGVYASVAKLRPWIDAKLK 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLAU	NP_002649.2	Binds urokinase plasminogen activator surface receptor. /evidence=ECO:0000250	34..57		2/5 (40%)
		KR	67..152	CDD:238056	18/97 (19%)
		Connecting peptide	152..177		6/27 (22%)
		Tryp_SPc	179..422	CDD:238113	82/269 (30%)
CG5390	NP_001285802.1	Tryp_SPc	153..391	CDD:238113	79/261 (30%)
		Tryp_SPc	153..390	CDD:214473	78/260 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910