Protein Alignment PITX3 and CG15696

DIOPT Version :10

• Sequence 1: NP_005020.1
• Gene: PITX3 / 5309
• HGNCID: 9006
• Length: 302
• Species: Homo sapiens
• Sequence 2: NP_650921.1
• Gene: CG15696 / 42469
• FlyBaseID: FBgn0038833
• Length: 179
• Species: Drosophila melanogaster
• Alignment Length: 141
• Identity: 38/141 - (26%)
• Similarity: 66/141 - (46%)
• Gaps: 31/141 - (21%)

Human     6 LSEAEARSPALSLSDAGTP----------H-PQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLK 59
            :|:....||..|.::|..|          | |:||.   ..::::.:::....||
  Fly    46 VSKESGGSPPASAAEAQIPVYDWLQYTRYHPPKLPR---ALRQNAPAKRTPGRLP---------- 97

Human    60 KKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQ 124
                  |..||.||||.||..::.:.|.......::|....||..||::||:||||: .:||:.:
  Fly    98 ------RIPFTPQQLQALENAYKESNYLSAEDANKLADSLELTNTRVKIWFQNRRAR-ERREKRE 155

Human   125 QAELCKGSFAA 135
            :.|.|..:|::
  Fly   156 KDESCDSTFSS 166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PITX3	NP_005020.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		14/75 (19%)
		Homeodomain	63..119	CDD:459649	21/55 (38%)
		OAR	258..275	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	262..275
		Nuclear localization signal. /evidence=ECO:0000255	268..272
CG15696	NP_650921.1	Homeodomain	95..144	CDD:459649	19/64 (30%)