Protein Alignment PITX3 and CG9876

DIOPT Version :10

• Sequence 1: NP_005020.1
• Gene: PITX3 / 5309
• HGNCID: 9006
• Length: 302
• Species: Homo sapiens
• Sequence 2: NP_611756.1
• Gene: CG9876 / 37668
• FlyBaseID: FBgn0034821
• Length: 275
• Species: Drosophila melanogaster
• Alignment Length: 158
• Identity: 58/158 - (36%)
• Similarity: 77/158 - (48%)
• Gaps: 29/158 - (18%)

Human    32 GCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIA 96
            ||.|.:.  ....|.:||.|.   |...:|.||.||.|:|.||..||..|:|..|||...|||:|
  Fly    92 GCGGADR--PAPCSGNLPAGG---GHHSRKPRRNRTTFSSAQLTALEKVFERTHYPDAFVREELA 151

Human    97 VWTNLTEARVRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPG------YSYGN 155
            ...:|:||||:|||:|||||:|:.|||..:..           |:....::.|.      :.|.|
  Fly   152 TKVHLSEARVQVWFQNRRAKFRRNERSVGSRT-----------LLDTAPQLVPAPISNNMHKYAN 205

Human   156 WP-PKALAPPLAAKTFPFAFNSVNVGPL 182
            .| |....||      |....::|.|||
  Fly   206 MPHPHPQPPP------PPGAYALNFGPL 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PITX3	NP_005020.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		14/38 (37%)
		Homeodomain	63..119	CDD:459649	32/55 (58%)
		OAR	258..275	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	262..275
		Nuclear localization signal. /evidence=ECO:0000255	268..272
CG9876	NP_611756.1	Homeodomain	118..174	CDD:459649	32/55 (58%)