Protein Alignment PITX3 and OdsH

DIOPT Version :10

• Sequence 1: NP_005020.1
• Gene: PITX3 / 5309
• HGNCID: 9006
• Length: 302
• Species: Homo sapiens
• Sequence 2: NP_523389.3
• Gene: OdsH / 32758
• FlyBaseID: FBgn0026058
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 149
• Identity: 55/149 - (36%)
• Similarity: 75/149 - (50%)
• Gaps: 16/149 - (10%)

Human     2 EFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQR 66
            |.|:...:|.|....|:|.....|.. ...|.|....|| |.|.::|   ...|.:...|:||.|
  Fly   103 ELGMDPHSEQRIKLDSVSPTHNIHAG-SSRGIKQDPLSD-EGADSNL---GQNDCTESSKKRRGR 162

Human    67 THFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQQA----- 126
            |:|.|.||:|||..||.:.|||:..||.:|...:|.|.|:.|||:||||||||:|.:::.
  Fly   163 TNFNSWQLRELERVFQGSHYPDIFMREALATKLDLMEGRIAVWFQNRRAKWRKQEHTKKGPGRPA 227

Human   127 -----ELCKGSFAAPLGGL 140
                 :.|.|. ..||..|
  Fly   228 HNAHPQSCSGD-PIPLSEL 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PITX3	NP_005020.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		21/68 (31%)
		Homeodomain	63..119	CDD:459649	31/55 (56%)
		OAR	258..275	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	262..275
		Nuclear localization signal. /evidence=ECO:0000255	268..272
OdsH	NP_523389.3	Homeodomain	159..215	CDD:459649	31/55 (56%)