Protein Alignment PIGA and Piga

DIOPT Version :10

• Sequence 1: NP_001427718.1
• Gene: PIGA / 5277
• HGNCID: 8957
• Length: 515
• Species: Homo sapiens
• Sequence 2: NP_001387965.1
• Gene: Piga / 363464
• RGDID: 1589723
• Length: 485
• Species: Rattus norvegicus
• Alignment Length: 516
• Identity: 429/516 - (83%)
• Similarity: 456/516 - (88%)
• Gaps: 32/516 - (6%)

Human     1 MACRGGAGNGHRASATLSRVSPGSLYTCRTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGH 65
            ||.|.|.|.|...|.:.|..|.|||.|.||.||||||||||||||||||||||||||||||||||
  Rat     1 MANRRGGGQGQPPSVSPSPGSSGSLSTDRTCTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGH 65

Human    66 KVIIVTHAYGNRKGIRYLTSGLKVYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSS 130
            |||.||||||||||:||||:|||||||||:||||||||||||||||||||||||||:||||||||
  Rat    66 KVITVTHAYGNRKGVRYLTNGLKVYYLPLRVMYNQSTATTLFHSLPLLRYIFVRERITIIHSHSS 130

Human   131 FSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLR 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 FSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLR 195

Human   196 AALNPEIVSVIPNAVDPTDFTPDPFRRHDS-ITIVVVSRLVYRKVDKACSWYNTSFDPPNNCRVD 259
            ||||||||||||||||||||||:||||||| ||:||||||||||
  Rat   196 AALNPEIVSVIPNAVDPTDFTPEPFRRHDSVITVVVVSRLVYRK--------------------- 239

Human   260 VIYMKLSLREGIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHK 324
                      |.||||||||||||||.:|||:||||||||||||||||||||||||:||||||||
  Rat   240 ----------GTDLLSGIIPELCQKYQELNFLIGGEGPKRIILEEVRERYQLHDRVQLLGALEHK 294

Human   325 DVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLPENLIILCEPSVKSLCEG 389
            ||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||
  Rat   295 DVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTKVGGIPEVLPENLIILCEPSVKSLCEG 359

Human   390 LEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDRVSVEAVLPMDKRLDRLISHCGPV 454
            |||||||:|||||||||||||:||||||||||||||||||:|||.|:||||.|||||||||||||
  Rat   360 LEKAIFQVKSGTLPAPENIHNVVKTFYTWRNVAERTEKVYERVSKESVLPMHKRLDRLISHCGPV 424

Human   455 TGYIFALLAVFNFLFLIFLRWMTPDSIIDVAIDATGPRGAWTNNYSHSKRGGENNEISETR 515
            ||||||||||.::||||||:||||||:|||||||||||.|||:.:...|:..||:::|::|
  Rat   425 TGYIFALLAVLSYLFLIFLQWMTPDSVIDVAIDATGPRRAWTHQWPRDKKRDENDKVSKSR 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIGA	NP_001427718.1	None
Piga	NP_001387965.1	GT4_PIG-A-like	34..433	CDD:340827	378/429 (88%)