Protein Alignment PIGA and Piga

DIOPT Version :10

• Sequence 1: NP_001427718.1
• Gene: PIGA / 5277
• HGNCID: 8957
• Length: 515
• Species: Homo sapiens
• Sequence 2: NP_035211.2
• Gene: Piga / 18700
• MGIID: 99461
• Length: 485
• Species: Mus musculus
• Alignment Length: 516
• Identity: 425/516 - (82%)
• Similarity: 453/516 - (87%)
• Gaps: 32/516 - (6%)

Human     1 MACRGGAGNGHRASATLSRVSPGSLYTCRTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGH 65
            ||.|.|.|.|...|.:.|..|.|:|...||.||||||||||||||||||||||||||||||||||
Mouse     1 MANRRGGGQGQPPSVSPSPGSSGNLSDDRTCTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGH 65

Human    66 KVIIVTHAYGNRKGIRYLTSGLKVYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSS 130
            |||.||||||||||:||||:|||||||||:||||||||||||||||||||||||||:||||||||
Mouse    66 KVITVTHAYGNRKGVRYLTNGLKVYYLPLRVMYNQSTATTLFHSLPLLRYIFVRERITIIHSHSS 130

Human   131 FSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLR 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 FSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLR 195

Human   196 AALNPEIVSVIPNAVDPTDFTPDPFRRHDS-ITIVVVSRLVYRKVDKACSWYNTSFDPPNNCRVD 259
            |||||||||||||||||||||||||||||| ||:||||||||||
Mouse   196 AALNPEIVSVIPNAVDPTDFTPDPFRRHDSVITVVVVSRLVYRK--------------------- 239

Human   260 VIYMKLSLREGIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHK 324
                      |.||||||||||||||.:|:|:||||||||||||||||||||||||:||||||||
Mouse   240 ----------GTDLLSGIIPELCQKYQELHFLIGGEGPKRIILEEVRERYQLHDRVQLLGALEHK 294

Human   325 DVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLPENLIILCEPSVKSLCEG 389
            ||||||||||||||||||||||||||||||||||||||:||||||||||:|||||||||||||:|
Mouse   295 DVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTKVGGIPEVLPESLIILCEPSVKSLCDG 359

Human   390 LEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDRVSVEAVLPMDKRLDRLISHCGPV 454
            |||||||:|||||||||||||:||||||||||||||||||:|||.|.||||.|||||||||||||
Mouse   360 LEKAIFQVKSGTLPAPENIHNVVKTFYTWRNVAERTEKVYERVSKETVLPMHKRLDRLISHCGPV 424

Human   455 TGYIFALLAVFNFLFLIFLRWMTPDSIIDVAIDATGPRGAWTNNYSHSKRGGENNEISETR 515
            |||:||||||.::||||||:||||||.|||||||||||.|||:.:...|:..||::||::|
Mouse   425 TGYMFALLAVLSYLFLIFLQWMTPDSFIDVAIDATGPRRAWTHQWPRDKKRDENDKISQSR 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIGA	NP_001427718.1	None
Piga	NP_035211.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		10/24 (42%)
		GT4_PIG-A-like	34..433	CDD:340827	375/429 (87%)