Protein Alignment SERPINI2 and Spn42Dd

DIOPT Version :9

• Sequence 1: NP_001012303.2
• Gene: SERPINI2 / 5276
• HGNCID: 8945
• Length: 405
• Species: Homo sapiens
• Sequence 2: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 396
• Identity: 123/396 - (31%)
• Similarity: 200/396 - (50%)
• Gaps: 36/396 - (9%)

Human     4 IFLWSLLLLFFGSQASRCSAQKNTEFAVDLYQEVSLSH-KDNIIFSPLGITLVLEMVQLGAKGKA 67
            ||||        ..:..|...|      ::||.:|.|| ..|::.||:.|..:|.||.:||:|..
  Fly     6 IFLW--------VTSVACQTSK------EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGST 56

Human    68 QQQIRQTL----KQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNK 128
            .::::..|    :.:|..|.....:|..    :..:::.....|||.:|:.:.:::.:.|....:
  Fly    57 AKELQSALGLPSEDKEAVAARYGALLND----LQGQEEGPILKLANRIYVNDQYSLNQNYNLAVR 117

Human   129 EFFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKF 193
            |.|:|..:.:...:....||.|:.||..:|.||||.|..........:.:|||||||||.|:.||
  Fly   118 EPFKSEAESISLTNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKF 182

Human   194 RKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMD 258
            ....|:...|......:|.:.||..:...:..||.:  |:.||:||.|.....|:.|.||.|...
  Fly   183 DPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLPREVEG 245

Human   259 IEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGI-TD 322
            :..:|     ::|:.:...:..:||.:.||:||:|.:.:.|:.|..|.|.|:|:...||||: .|
  Fly   246 LSALE-----EKIVGFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFAD 305

Human   323 SSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFI-ANHPFLFIMKHNPTESILFM 386
            .|...||||:.|.|.|:||:|:|||.:|.  :.|......|.|: |:|||.|:::  ...:|.|.
  Fly   306 KSGGKVSQVSHKAFLEVNEEGAEAAGATS--VAVTNRAGFSTFLMADHPFAFVIR--DANTIYFQ 366

Human   387 GRVTNP 392
            |||.:|
  Fly   367 GRVVSP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINI2	NP_001012303.2	serpinI2_pancpin	23..392	CDD:381042	117/375 (31%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	115/373 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9820
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.930