Protein Alignment SERPINI2 and Spn75F

DIOPT Version :10

• Sequence 1: NP_006208.1
• Gene: SERPINI2 / 5276
• HGNCID: 8945
• Length: 405
• Species: Homo sapiens
• Sequence 2: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Alignment Length: 371
• Identity: 75/371 - (20%)
• Similarity: 151/371 - (40%)
• Gaps: 49/371 - (13%)

Human    29 FAVDLYQEVSLSH-KDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEEFFVLKSF 92
            |.::|.:::|... ..|.::||:.|...|.::.|.......||:...|  |.|...:|..:  |.
  Fly    22 FEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESAL--QLTGLNQEEII--SL 82

Human    93 FSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKACAEMISTWVER- 156
            |....||..:..|.:.|.:||...:..... :....|.....:|.:.|...::.|..|..|:.:
  Fly    83 FKEAREKVAQEQFTMGNRIYLSPDYNASPN-ITQLSENLGVEVKNMTFSGDQSAASEIKKWLNKW 146

Human   157 --KTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTKKNGSTVKIPMMKAL 219
              |..|   ::|...:....|::|.|..:.:...||.:    :|.|.|.|    .|:.....|..
  Fly   147 IGKAGG---NLFGKNDISQTTQIVAVQGMSYSCVWKNR----ETALTNRT----FTLLRQNKKPF 200

Human   220 LRTKYGYFSESSLNY----QV--LELSYKGDEFSLIIILPAEGMDIEEVEKLITAQQILKWLSEM 278
            :.|....::|:.:::    ||  :.:.:|..:..::::||......:::  |.:...||| :...
  Fly   201 VYTTQMMYTEAPMDFFNNDQVRGVMVPFKNSDMGMLVLLPRPRYSTQQI--LYSLDTILK-IKLR 262

Human   279 QEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDG 343
            :.::..:.||:|||.:.||....|.:|.|..:|: ..:.:.....:.....|....:..::.:|.
  Fly   263 RSKKTHLFLPKFKVSESVDLNMALKALGIQNLFT-NTNAANFKQYNSFDADQNRVLMTIDVGDDF 326

Human   344 SEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTESILFMGRV 389
            .:...                 ..|..|:|::|...|  |..:||:
  Fly   327 DDRVV-----------------YVNRGFVFVVKDKST--IYMIGRM 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINI2	NP_006208.1	serpinI2_pancpin	23..392	CDD:381042	75/371 (20%)
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	73/368 (20%)