Protein Alignment SERPINB13 and Spn42Dd

DIOPT Version :9

• Sequence 1: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Sequence 2: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 398
• Identity: 123/398 - (30%)
• Similarity: 207/398 - (52%)
• Gaps: 40/398 - (10%)

Human     6 AVSTRLGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIK 69
            :|:.:...::::.|.|:: :.|:..|||.|.|.:.||.:|..|:||.:|:
  Fly    12 SVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQ--------------- 61

Human    70 AEEKEVVRIKAEGKEIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVE 134
                     .|.|...|:.|||..::...|.::........|.:.||::....|...|.|...|.
  Fly    62 ---------SALGLPSEDKEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVR 117

Human   135 KYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDRE 199
            :.:.:..|.:...| ...:.::||.||..:|:.|||.:...||::|..|.:|||.:||||||:.:
  Fly   118 EPFKSEAESISLTN-GPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESK 181

Human   200 FKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGL 264
            |....|:...|.:..:.|..||||.|..:|...:..||.|:::.:||.|::|||.:.||.:::||
  Fly   182 FDPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGL 246

Human   265 EKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGM- 328
            ..:     .||:|.:..|  :..::|.|.||:|::|...:|:..|..:|:.:.|:: |:|.||:
  Fly   247 SAL-----EEKIVGFARP--LVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTD-KSDLSGLF 303

Human   329 SSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPGHEN-VHCNHPFLFFIRHNESNSIL 392
            :..||....:..|.:|:.|.|||.|||.||.:  .||:..|... :..:|||.|.||  ::|:|.
  Fly   304 ADKSGGKVSQVSHKAFLEVNEEGAEAAGATSV--AVTNRAGFSTFLMADHPFAFVIR--DANTIY 364

Human   393 FFGRFSSP 400
            |.||..||
  Fly   365 FQGRVVSP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB13	NP_001294852.1	SERPIN	4..400	CDD:294093	121/396 (31%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	119/389 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.880