Protein Alignment SERPINB13 and Spn42Da

DIOPT Version :10

• Sequence 1: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Sequence 2: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Alignment Length: 378
• Identity: 121/378 - (32%)
• Similarity: 182/378 - (48%)
• Gaps: 43/378 - (11%)

Human    26 NIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEKEVVRIKAEGKEIENTEA 90
            ||.|||..|.|...|..||....||:||::                        ..|....:.|.
  Fly    64 NIVFSPFSIQTCAAMARLGAENETATQLDQ------------------------GLGLASSDPEQ 104

Human    91 VHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDF---VNAADE 152
            :...|.:.|   :...:...|.|.|::|....|...|::...:.|.:.::.:.|||   |.||
  Fly   105 IAHSFHQVL---AAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAA-- 164

Human   153 SRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFWMNKSTS 217
              ..||:|||.:||..||||.|...::|.::|||||.::|||.|..:|.|..|:.:.|.::...:
  Fly   165 --ATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGERT 227

Human   218 KSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSP 282
            ..|.||:....|.:..|..|.|..|.:|||::||||.::|||...||..:.:|:....|.:.|.
  Fly   228 VQVPMMSLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQ- 291

Human   283 GHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGM-SSGSGLYAQKFLHSSFVA 346
             .:.|.||.|.||||:.|...:|..|...:||...||: :|::..| .|...|.....:|.:|:.
  Fly   292 -SLYETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSD-QAEFGKMLQSPEPLKVSAIIHKAFIE 354

Human   347 VTEEGTEAAAATGIGF----TVTSAPGHENVHCNHPFLFFIRHNESNSILFFG 395
            |.|||||||||||:..    .:.|.........:|||.:.:.| :.:..||:|
  Fly   355 VNEEGTEAAAATGMAVRRKRAIMSPEEPIEFFADHPFTYVLVH-QKDLPLFWG 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB13	NP_001294852.1	serpinB13_headpin	1..400	CDD:381038	121/378 (32%)
Spn42Da	NP_524955.2	serpin42Da-like	45..407	CDD:381065	121/378 (32%)