Protein Alignment SERPINB13 and Spn27A

DIOPT Version :10

• Sequence 1: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Sequence 2: NP_652024.1
• Gene: Spn27A / 45815
• FlyBaseID: FBgn0028990
• Length: 447
• Species: Drosophila melanogaster
• Alignment Length: 397
• Identity: 107/397 - (26%)
• Similarity: 188/397 - (47%)
• Gaps: 58/397 - (14%)

Human    21 KTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEKEVVRIKAEGKEI 85
            :|.|.|:..||..:...:.::.......|.:|:|                       :.....:|
  Fly    88 ETADKNVIISPFSVKLVLALLAEAAGAGTQTQVE-----------------------LANTQTDI 129

Human    86 ENTEAVHQQFQKFLTEISKLTNDYE-LNITNRLFGEKTYLFLQKYLDYVEKYYHASLEPVDFVN- 148
            .:...|.:.::|.|....|....:| |::..:||.:......||:...::.:|.:.:|.:||.|
  Fly   130 RSQNNVREFYRKTLNSFKKENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTNP 194

Human   149 --AADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKENTKEEKFW 211
              |||    .||:|..:.|..:::.|....::.||. ::|.|::||.|.|.|:|  ..|.:..|:
  Fly   195 EAAAD----AINAWAANITQGRLQQLVAPDNVRSSV-MLLTNLIYFNGLWRRQF--ATTFQGSFF 252

Human   212 MNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPNDIDGLEKIIDKISPEKL 276
            .:|......:.|.|:..|.:|..|.|:|:||.:|||..: |:|||||..::|:..::..:..::|
  Fly   253 RSKDDQSRAEFMEQTDYFYYTTSEKLKAQILRLPYKGKN-SLFVLLPYALNGIHDLVKNLENDEL 316

Human   277 --VEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSEHKADYSGMSSGSGLYAQ-- 337
              .:|.    |||.||.:.||:|..:...:|:..|.::|:.:.| |..|...|::.|:.:..:
  Fly   317 KSAQWA----MEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIF-EDSASLPGLTRGADVAGKVK 376

Human   338 --KFLHSSFVAVTEEGTEAAAATGI-------GFTVTSAPGHENVHCNHPFLFFIRHNESNSILF 393
              ..|..:.:.|.|:||||.|||.:       |.|..     |..:.|.||:|||....:.:|||
  Fly   377 VSNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAI-----EEFNVNRPFVFFIEEESTGNILF 436

Human   394 FGRFSSP 400
            .|:..||
  Fly   437 AGKVHSP 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB13	NP_001294852.1	serpinB13_headpin	1..400	CDD:381038	105/395 (27%)
Spn27A	NP_652024.1	serpinK_insect_SRPN2-like	64..443	CDD:381044	105/395 (27%)