Protein Alignment SERPINB13 and Spn88Eb

DIOPT Version :10

• Sequence 1: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Sequence 2: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Alignment Length: 414
• Identity: 116/414 - (28%)
• Similarity: 202/414 - (48%)
• Gaps: 65/414 - (15%)

Human    15 LFKELKKT-NDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAEEKEVVRI 78
            |.|::::. ..||:||||.....|:              |...|.|.::|        |:|:.:.
  Fly    45 LMKQIREIYPSGNLFFSPFSTYNAL--------------LLAYFSSSEQT--------ERELAQA 87

Human    79 KAEG-----KEIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYH 138
            ...|     :::..:..:.|:..:|....|.:    ||:..||:|.::|.....|:...:   |.
  Fly    88 LNLGWALNKQQVLVSYTLAQRQDEFRWRQSPM----ELSSANRIFVDRTINVSNKFNTLL---YG 145

Human   139 ASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREFKKE 203
            |:.| :||.|..:...|:||.|:..||:.:|:|:.....|:..|.|||.|..|.||||..:||.|
  Fly   146 ATKE-LDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVE 209

Human   204 NTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYK---------------NNDLSM 253
            .|..:.|::|:...:.|.||.::.:|..|..|.||::|:.:||:               .:|:||
  Fly   210 ETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISM 274

Human   254 FVLLPNDID-GLEKIIDKISPEKLVEWTSPGHMEER----KVNLHLPRFEVEDGYDLEAVLAAMG 313
            .::|||... .|.::|.:::.:.:.:|.      ||    |:.|.||:|:.|...:|..:|:.||
  Fly   275 IIILPNSNKISLNRVISRLNADSVKKWF------ERALPQKIELSLPKFQFEQRLELTPILSLMG 333

Human   314 MGDAFSEHKADYSGMSSGS-GLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTS-APGHENVHCN 376
            :...|:.: |.:..:::.. .|......|.:.:.|.|.|:.|||||.:..:.:| .|.....:||
  Fly   334 VNTMFTRN-ATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCN 397

Human   377 HPFLFFIRHNESNSILFFGRFSSP 400
            |||:|.|...:.::|||.|.:|.|
  Fly   398 HPFVFLIYDEKVDTILFAGVYSDP 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB13	NP_001294852.1	serpinB13_headpin	1..400	CDD:381038	115/412 (28%)
Spn88Eb	NP_650427.1	serpin_crustaceans_chelicerates_insects	34..421	CDD:381059	115/412 (28%)