Protein Alignment SERPINB13 and Spn43Ad

DIOPT Version :10

• Sequence 1: NP_001294852.1
• Gene: SERPINB13 / 5275
• HGNCID: 8944
• Length: 400
• Species: Homo sapiens
• Sequence 2: NP_610261.1
• Gene: Spn43Ad / 35639
• FlyBaseID: FBgn0044011
• Length: 407
• Species: Drosophila melanogaster
• Alignment Length: 402
• Identity: 94/402 - (23%)
• Similarity: 166/402 - (41%)
• Gaps: 61/402 - (15%)

Human     8 STRLGFDLFKELKKTN-DGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
            |.|.|..|..:|..|. |.|:..||:.|..|:.::...:.....|||.:.
  Fly    36 SNRFGLRLTTKLGLTQPDANVVVSPLLIQAALSLLYAESSSEYGSQLRQA--------------- 85

Human    72 EKEVVRIKAEGKEIENTEAVH-----QQFQKFLTEISK-LTNDYELNITNRLFGEK--TYLFLQK 128
                         :|.|.|.|     |.|:..||::.: ......|.:.:.|:.::  |:.|..:
  Fly    86 -------------LELTHASHPKLAVQDFETLLTDLKQSAAIGCRLRLLSDLYAQQRFTFNFRNE 137

Human   129 YLDYVEKY----YHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISS----STKLV 185
            :.....:.    :..|.|...  |||.:    ||....|::|..:.:|.....:.|    :|..:
  Fly   138 FETLAARMGVGCHRLSWESAS--NAAQD----INYAFLSRSNFSLGELVSAPQLESLAEHNTPFL 196

Human   186 LVNMVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNND 250
            .|:.|.|:..|...|....|:...|:...:..:.|..|...|.:.:..:..|.|:::.:|:...|
  Fly   197 HVSGVTFRAPWAWAFDPTETQSINFFAGGNRPRLVDAMFGQHRYRYAEVPALDAQLIEVPFATAD 261

Human   251 LSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMG 315
            |.|.::.||..|||.::..|::...|.:..|  .:|||||.|.||:..|....||:.||..:|:.
  Fly   262 LRMLIVFPNRPDGLAQLERKLAQSDLHQLRS--QLEERKVALTLPKLRVLVHSDLKHVLEELGLA 324

Human   316 DAFSE--HKAD-YSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSA-PGHENVHCN 376
            ..|:.  |.:: :|.:.|.|.......:.|..:.:.|:|..|..:...|.....| |    :..|
  Fly   325 KLFTSEVHLSEVFSSILSSSAPPLGAVVQSGLLELQEDGGNADDSFSFGDLFRRALP----LVIN 385

Human   377 HPFLFFIRHNES 388
            |||.:.|.:.::
  Fly   386 HPFFYAIGNGKT 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB13	NP_001294852.1	serpinB13_headpin	1..400	CDD:381038	94/402 (23%)
Spn43Ad	NP_610261.1	serpin42Dd-like_insects	34..407	CDD:381070	94/402 (23%)