Protein Alignment SERPINI1 and nec

DIOPT Version :9

• Sequence 1: NP_001116224.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Alignment Length: 391
• Identity: 107/391 - (27%)
• Similarity: 191/391 - (48%)
• Gaps: 45/391 - (11%)

Human    30 SVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKEFS 94
            |..::..:..:...:|::|||.|:...:.::...:.|.|.:|::        |.||   |.|  :
  Fly   111 SSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQ--------KAGE---FSK--N 162

Human    95 NMVTAKESQYVMK-----------IANSLFVQNGF-HVNEEFLQMMKKYFNAAVNHVDFSQNVAV 147
            .|..|::.:.|:|           :|..::..... .||..:.:..|.||:|....||.......
  Fly   163 AMAVAQDFESVIKYKKHLEGADLTLATKVYYNRELGGVNHSYDEYAKFYFSAGTEAVDMQNAKDT 227

Human   148 ANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEV 212
            |..||.||.:.|.|.::|||:|.|.|..|...|:|||||:|.|:.:|...:|..:.|...:....
  Fly   228 AAKINAWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRIS 292

Human   213 QIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLA-TLEPLVKAQL- 275
            ::.||:....:...|..    |.|.  ..||:.|:....||:::|..:...|. .|:.|.:.:.
  Fly   293 KVAMMFNDDVYGLAELP----ELGA--TALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEFD 351

Human   276 VEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLSDNKEIFLSKAIHKS 340
            :...|:.:::|.|.|.||:|..|.|.|:.:.||.||:.::|..::.:|.|.| :.:.:||.:.|:
  Fly   352 LNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMD-QPVRVSKILQKA 415

Human   341 FLEVNEEGSEAAAVS--GMIAISRMAVLYP---QVIVDHPFFFLIRNRRTGTILFMGRVMHPETM 400
            ::.|.|.|:||:|.|  ..:.:|    |.|   :.:.:.||.|.:|.  ..::||:|.|.:|..|
  Fly   416 YINVGEAGTEASAASYAKFVPLS----LPPKPTEFVANRPFVFAVRT--PASVLFIGHVEYPTPM 474

Human   401 N 401
            :
  Fly   475 S 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINI1	NP_001116224.1	neuroserpin	23..410	CDD:239003	107/391 (27%)
nec	NP_524851.1	SERPIN	108..468	CDD:238101	104/382 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.830