Protein Alignment SERPINI1 and Spn53F

DIOPT Version :10

• Sequence 1: NP_005016.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Alignment Length: 403
• Identity: 92/403 - (22%)
• Similarity: 173/403 - (42%)
• Gaps: 48/403 - (11%)

Human     9 LLVLQSMA-----TGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGST 68
            ||:|..::     ..:..|:|..|.:..:..||        ||:||...|..:|..:.:|.:...
  Fly     5 LLILLGISRYRAQKNSQLPDELYAAIVNSFSNR--------NIMFSTEMIRSSMLFIYVGVEEDE 61

Human    69 QKEIRHSMGYDSLKNGEEFSFLKEFSNMVTAK--ESQYVMKIANSLFVQNGFHVNEEFLQMMKKY 131
            .::||.:|.|    .|...|..|..:..:.|.  :...|.|.....:|:....::.|:...|:
  Fly    62 SEQIRKAMHY----RGTHLSEYKPKTQKIFAMSVKKAPVAKSLTRFYVRQNMKMSTEYRVFMR-- 120

Human   132 FNAAVNHVD-FSQNVAVA----NYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWK 191
                  |.: .::|:|.|    :.:|.:..:.....:..:|....:...:...|:||::|..:|:
  Fly   121 ------HTEGRARNIAFAREQLDEVNTFYSHEMGEQIGQVVKESWWKPNSQGLLVNAIFFNLSWE 179

Human   192 SQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLV 256
            ..|.||.|....|..:....|.||||::..:|.:|..  |:.:|..:.    :|:...::.|:|:
  Fly   180 RTFNPEATYPREFRVNATKSVMIPMMHEDSKFAFGIL--GNLKATAVL----VPFSHGDLRMLLI 238

Human   257 LSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDAN 321
            ...|...||.|:..::|..:...|.::....|.|.:|:|.:..:::|....:.:||.:||....:
  Fly   239 KPDQPDGLAALQMKLQAMNILSVARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKS 303

Human   322 L-TGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAV---SGMIAISRMAVLYPQVIVDHPF-FFLIR 381
            . |.|..|....:...||....|..|:|....:.   :|.:..:...|.|  .:..||| |::|.
  Fly   304 FSTLLHRNTNFRIDGVIHVVTFEFQEQGIGTPSTDVGNGSLTHTFNGVKY--FLATHPFAFYIID 366

Human   382 NRRTGTILFMGRV 394
            |.   :|.|.|.|
  Fly   367 NT---SIYFAGHV 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINI1	NP_005016.1	serpinI1_NSP	23..394	CDD:381005	87/382 (23%)
Spn53F	NP_001036553.1	serpin42Dd-like_insects	20..379	CDD:381070	89/388 (23%)