Protein Alignment SERPINB10 and Spn42Dd

DIOPT Version :10

• Sequence 1: NP_005015.1
• Gene: SERPINB10 / 5273
• HGNCID: 8942
• Length: 397
• Species: Homo sapiens
• Sequence 2: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 392
• Identity: 125/392 - (31%)
• Similarity: 196/392 - (50%)
• Gaps: 39/392 - (9%)

Human    10 QFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCDPESEK 74
            |.:.|:.:.|::|...:|:..|..||.|.|::|::||:|:||.::...|..         |..:|
  Fly    16 QTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGL---------PSEDK 71

Human    75 KRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLEDMKTYFGAEPQ 139
                       |.:.:.:..|::::....:..:||.||.||....|:.:..|...::..|.:|.:
  Fly    72 -----------EAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAE 125

Human   140 PVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTE 204
            .::.........: ||.||..||.|||:.::...|:.|..:.:||||:||||.||.:|....|..
  Fly   126 SISLTNGPVAAER-INQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRA 189

Human   205 KPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRDLSLLILLPEDINGLEQLEKAIT 269
            ..|::....|.|||||.........:.....|..::|.|.:.:||:.|.||.::.||..||:.|.
  Fly   190 STFQVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEKIV 254

Human   270 YEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGM----SSARN 330
                   ..|..:...||.|.|||||:|...:||.||..:|:.:.|: .|:|.||:    |..:
  Fly   255 -------GFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFT-DKSDLSGLFADKSGGK- 310

Human   331 LFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLC 395
              :|.|.||||:|:||:|.|||..:...:..|... |....|:|||.|.||  ..|||.|.||:.
  Fly   311 --VSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGF-STFLMADHPFAFVIR--DANTIYFQGRVV 370

Human   396 SP 397
            ||
  Fly   371 SP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB10	NP_005015.1	serpinB10_bomapin	1..397	CDD:381035	123/390 (32%)
		Nuclear localization signal	74..77		1/2 (50%)
Spn42Dd	NP_001163067.1	serpin42Dd-like_insects	12..372	CDD:381070	123/390 (32%)