Protein Alignment SERPINB8 and Spn28F

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Alignment Length: 387
• Identity: 135/387 - (34%)
• Similarity: 209/387 - (54%)
• Gaps: 27/387 - (6%)

Human     1 MDDLC------EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALC 59
            |..||      ..:..||...:::|.:|:.:.|:..||:|:..||:|.:|||:..||.:|...|.
  Fly     1 MKHLCLLLLATSVSCRFADDFYQLLAKENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLK 65

Human    60 LYKD-GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123
            |..| .::...::.|||::........|..|||::..|....:|.:.:..:..:.||.|.:...
  Fly    66 LPDDKKEVAAKYKDLLSKLEGREKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIV- 129

Human   124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTN 188
            |..:....:|:||..:|.|||.:::.:..:..: :|:::|||||||:|..:|:.|.|:...|:.:
  Fly   130 DPNKASSIVNNWVDNQTRGKIKDLVSSNDMSKM-ELIVLNAIYFKGQWEYKFNPKLTKKRNFRVS 193

Human   189 EEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKA 252
            ::|.. |:||.....|:..:..|:..:::||||....|||:|.|||....|:.:||.:.  .||
  Fly   194 DQKSVPVEMMSLFQSFRAAHDSELGAKIIELPYRNSSLSMLIFLPDQVDGLSELEKKIV--GFK- 255

Human   253 WTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKC 317
                .||:|..|.:.||:.|:|....|...|..:|:.||| |..|||..:....||.:.||.||.
  Fly   256 ----PKLSKMDVTLRLPKFKIEFFAQLNKVLVAMGIQDAF-EKSADFKDLVENSNVHVKKVIHKA 315

Human   318 FVEVNEEGTEAAAATAV--VRNSR---CSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
            |:||||||.|||||||:  ||.|.   .|:|.  |.|||||.:.||..:|  |.|.|.|..|
  Fly   316 FIEVNEEGAEAAAATALLFVRYSMPMPSSQMV--FNADHPFAYVIRDRET--IYFQGHFVKP 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	134/385 (35%)
Spn28F	NP_524957.2	serpin42Dd-like_insects	12..373	CDD:381070	131/374 (35%)