Protein Alignment SERPINB8 and Spn42Da

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Alignment Length: 368
• Identity: 128/368 - (34%)
• Similarity: 196/368 - (53%)
• Gaps: 18/368 - (4%)

Human    11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDG--DIHRGFQSL 73
            |:|:::..|..:....|:.|||.||.:..||..:||:..||.|:.|.|.|....  .|...|..:
  Fly    48 FSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLGLASSDPEQIAHSFHQV 112

Human    74 LSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAE 138
            |:...   ...:||.||::|.........:|.:...|.:.:..:.:.|:::.:.... ||:||.:
  Fly   113 LAAYQ---DSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQAAAT-INNWVEQ 173

Human   139 KTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKTVQMMFKEAKF 203
            :|...|.:::.|..::..::|||||||:|||.|..||.:..||...|..:.| :|||:.....|.
  Fly   174 RTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHLDGE-RTVQVPMMSLKE 237

Human   204 KMGYAD--EVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQV 266
            :..|||  .:....|||||.:.:|||:|:||:..|.|..:|:.|........|.|  |.::||.:
  Fly   238 RFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQS--LYETKVAL 300

Human   267 FLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGM-STEKNVPLSKVAHKCFVEVNEEGTEAAA 330
            .|||.|.|...:|....::|||...|.: :|:|..| .:.:.:.:|.:.||.|:|||||||||||
  Fly   301 KLPRFKAEFQVELSEVFQKLGMSRMFSD-QAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAA 364

Human   331 ATAV-VRNSRC--SRMEP-RFCADHPFLFFIRHHKTNCILFCG 369
            ||.: ||..|.  |..|| .|.|||||.:.:.|.| :..||.|
  Fly   365 ATGMAVRRKRAIMSPEEPIEFFADHPFTYVLVHQK-DLPLFWG 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	128/368 (35%)
Spn42Da	NP_524955.2	serpin42Da-like	45..407	CDD:381065	128/368 (35%)