Protein Alignment SERPINB8 and nec

DIOPT Version :9

• Sequence 1: NP_001353127.1
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Alignment Length: 387
• Identity: 109/387 - (28%)
• Similarity: 186/387 - (48%)
• Gaps: 48/387 - (12%)

Human    11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDG-DIHRGFQSLL 74
            |:..|||.:.:..:.:||.|||.|:.:.||:::..:.|.|..::.:|....|:. .:.:.|:|::
  Fly   110 FSSELFKEIIKSQSQQNVVFSPFSVHALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESVI 174

Human    75 S-EVNRTGTQYLLRTA---NRLFGEKTCDFLPDFKEYCQKFYQA--ELEELSFAEDTEECRKHIN 133
            . :.:..|....|.|.   ||..|...    ..:.||.:.::.|  |..::..|:||   ...||
  Fly   175 KYKKHLEGADLTLATKVYYNRELGGVN----HSYDEYAKFYFSAGTEAVDMQNAKDT---AAKIN 232

Human   134 DWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQF--------DRKYTRGMLFKTNEE 190
            .||.:.|..||.:::....|||.|:.:||||:||:|:|..:|        |.::|.|.:.|
  Fly   233 AWVMDTTRNKIRDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISK---- 293

Human   191 KKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTN 255
               |.|||.:..:.:....|:....|||.|.:...||:||||::.|.|..:.:.|:..:|.....
  Fly   294 ---VAMMFNDDVYGLAELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEFDLNRV 355

Human   256 SEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVE 320
            :.:|.:..|.|.||:.:.|...|:...|:.||:...|.........|  ::.|.:||:..|.::.
  Fly   356 AHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLM--DQPVRVSKILQKAYIN 418

Human   321 VNEEGTEAAAATAVVRNSRCSRMEP--------RFCADHPFLFFIRHHKTNCILFCGRFSSP 374
            |.|.||||:||:       .::..|        .|.|:.||:|.:|...:  :||.|....|
  Fly   419 VGEAGTEASAAS-------YAKFVPLSLPPKPTEFVANRPFVFAVRTPAS--VLFIGHVEYP 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_001353127.1	SERPIN	4..374	CDD:320777	108/385 (28%)
nec	NP_524851.1	SERPIN	108..468	CDD:238101	108/382 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930