Protein Alignment SERPINB8 and Spn43Aa

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_524805.1
• Gene: Spn43Aa / 45041
• FlyBaseID: FBgn0024294
• Length: 390
• Species: Drosophila melanogaster
• Alignment Length: 369
• Identity: 123/369 - (33%)
• Similarity: 196/369 - (53%)
• Gaps: 23/369 - (6%)

Human    11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKDGDIHRGFQ 71
            ||..||:.|..:....||..||:||..||.:.:.||:|.|||::.:.|..    .||| :...:.
  Fly    30 FATELFQTLATDRQDENVIISPVSIQLALGLAYYGAEGRTAAELQKTLHASAKESKDG-LAESYH 93

Human    72 SLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWV 136
            :||....::.|  :|..||:::..:.......|:|..||::.:|:|.|.|:.:||.. :.||.||
  Fly    94 NLLHSYIKSKT--VLEIANKVYTRQNLTVSSHFREVAQKYFDSEVEPLDFSRETEAV-EQINRWV 155

Human   137 AEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKK-TVQMMFKE 200
            .::||.||..|::  :::|.|.:.||||||||.:|...|:.:.||...|..:|.:. .|..||.:
  Fly   156 KQQTENKIERVVE--SLEPDTNVALVNAIYFKARWARPFNDEDTRDREFWLSESRSIQVPTMFAD 218

Human   201 AKFKMGYAD--EVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSK 263
            ..:.  |||  |:..:.:||.:....|:|..:||:..:.|..:|:.|....|...  .::.....
  Fly   219 NWYY--YADYPELDAKAIELFFENINLTMWFILPNQRSGLQALEQKLKGVDFNLL--EDRWQWQS 279

Human   264 VQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNV--PLSKVAHKCFVEVNEEGT 326
            |.|:||:.|.|...||.|.|.::|:...|.:| ||||.:..:..:  .::||.||.|::|||.|.
  Fly   280 VSVYLPKFKFEFDTDLRPTLHKMGISAMFSDA-ADFSNIFQDSPIGTRITKVQHKTFIDVNEIGC 343

Human   327 EAAAATAVVRNSRCSRMEPR-FCADHPFLFFIRHHKTNCILFCG 369
            |||.|:..........::|: |.|||||.|.||  ..:.:.|.|
  Fly   344 EAAGASYAAGVPMSLPLDPKTFVADHPFAFIIR--DKHAVYFTG 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	123/369 (33%)
Spn43Aa	NP_524805.1	serpin42Dd-like_insects	27..390	CDD:381070	123/369 (33%)