Protein Alignment SERPINB8 and Spn43Ab

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Alignment Length: 382
• Identity: 104/382 - (27%)
• Similarity: 182/382 - (47%)
• Gaps: 27/382 - (7%)

Human     3 DLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIH 67
            |........|..|:..:..:..:.||..||.:|.|::|:.|:||||.||:::.|.|.| ..||..
  Fly    24 DAAADRNLLAADLYNAVAADHLNENVVISPATIQSSMALAFVGAKGQTASELQQGLRL-GPGDAD 87

Human    68 R------GFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAED-T 125
            .      .:|..|:..|.      .|.||.::..:..:|...|::..|:.:.:.:::|.|... .
  Fly    88 AVSQRSGSYQQALTRDNN------FRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYN 146

Human   126 EECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNE- 189
            :.....||..||.||.|||:::|.|..::..|:.|:||.:.:...|.:.|....|....|:|..
  Fly   147 KRTADGINRAVATKTNGKITDILRAELLNDRTEGVIVNGVSYSAAWQKAFRLDKTEKRSFRTGSG 211

Human   190 EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWT 254
            :...|..|:....|.....:.:..:|:||||...:.||::|||:....|..::::|:.:...|..
  Fly   212 QSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDFSMLLLLPNRKDGLRSLQQSLSGKNLLAEI 276

Human   255 NSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGM-STEKNVPLSKVAHKCF 318
            .:  :::.||:|.||:..:.....||...::||:...|.. ..||..| ....:..::.|.||..
  Fly   277 GA--MSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMFSR-DGDFGNMYRMFVSHFINAVEHKAN 338

Human   319 VEVNEEGTEAAAATAVVRN--SRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSS 373
            |||.|.|.:....|.:::.  ||..:.|    |||||:|.|::  .:.|.|.|..::
  Fly   339 VEVTEAGVDQPLETGLLKGLFSRSKKFE----ADHPFVFAIKY--KDSIAFIGHIAN 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	104/382 (27%)
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	103/379 (27%)