Protein Alignment SERPINB8 and Spn77Bc

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_649207.1
• Gene: Spn77Bc / 40236
• FlyBaseID: FBgn0036970
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 395
• Identity: 94/395 - (23%)
• Similarity: 161/395 - (40%)
• Gaps: 56/395 - (14%)

Human     1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKD-G 64
            :..:.:|...||::|.::.....|..|...:|.|..|.:.|.:.||:|:|..|:...|.:|.| .
  Fly    30 LQKMTDARLQFALNLLQMESTHLNLENFAMTPFSTWSLMIMFYEGAEGTTLKQIRDVLAIYVDYP 94

Human    65 DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTC--DFLPDFKEYCQKFYQAELEELSFAEDTEE 127
            .:.|.::.:      ....||.....:||..:..  |.:.|. |..:.:....||  ...|....
  Fly    95 TLRRWYEDV------RAYHYLNSENTKLFSLRYAYYDDVGDL-ELVKGYNSVVLE--GVGEGNVV 150

Human   128 CRKH--------------INDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRK 178
            .|:.              |||.:.:.:..||.......:.:....::.:...|||.||...||:.
  Fly   151 LREGRPRGVDFDQGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKS 215

Human   179 YTRGMLFKT--NEEKKTVQMMFKEAKFKMGYADEV---HTQVLELPYVEEELSMVILLPDDNTDL 238
            .|:...|..  ......|:||.:..|:  .|.:.|   ...|||||:.|.||.|:::||..:..:
  Fly   216 QTKVEQFYNAGGSPAGKVEMMVQTGKY--AYVNNVKGLQADVLELPFGEHELVMIVILPKPSQRV 278

Human   239 AVVEKAL-------TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296
            ::|.|.|       ..|:.:|..|     :|.|:|.||:........||..:...|:.|..:|.
  Fly   279 SLVLKQLKNLGLHRLLEELEASKN-----ESDVEVKLPKFDTRSVLSLEDTVYEAGLTDLRNEF- 337

Human   297 ADFSGM---STEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFI- 357
            ||...|   :.::...||.......:.|:|||...|...   ::|..:.:  :|..:.||.:.:
  Fly   338 ADLGRMLIPTGDRGAYLSLYHQFARIVVDEEGLPNAVPQ---KSSGTNNI--KFHINRPFAYLVL 397

Human   358 -RHHK 361
             |.||
  Fly   398 QRTHK 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	94/395 (24%)
Spn77Bc	NP_649207.1	serpin	33..412	CDD:476815	94/392 (24%)