Protein Alignment SERPINB8 and Spn77Ba

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_649205.3
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Alignment Length: 386
• Identity: 104/386 - (26%)
• Similarity: 182/386 - (47%)
• Gaps: 39/386 - (10%)

Human    11 FAISLFKILGEEDNSRNVFF--SPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIHRGFQSL 73
            ||:.|.:.:..|....|..|  ||.|:.|.|.:::.|::|.|..|:.::|.:..:.:..||...:
  Fly    79 FALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLRINVEDEKLRGAYKV 143

Human    74 LSE-VNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVA 137
            .|. :|.|.:...:.|...::..|......::::..|.:....:|...::.|:.   ..||:...
  Fly   144 WSSFLNITTSTIEVATLQAIYTGKGYPIKNNYRDAIQNYNVQPMEVDFYSPDSV---IQINEDTN 205

Human   138 EKTEGKISEVLDAGTVDPL----TKLVLVNAIYFKGKWNEQFDRKYTRGMLF--KTNEEKKTVQM 196
            ..|.|.|..     |:.|.    .|:.|::::||||:|...|::..||...|  ::.|....:.|
  Fly   206 RTTRGLIPY-----TILPQDVYGAKMFLLSSLYFKGQWKFPFNKTLTREEPFFSESGEVIGKIPM 265

Human   197 MFKEAKFKMGYADEVH---TQVLELPY-VEEELSMVILLPDDN---TDLAVVEKAL----TYEKF 250
            |.:||.|  .|...|.   ..|||||| .::.|:|:::||...   .|:|...|||    ..::.
  Fly   266 MVQEANF--AYVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRL 328

Human   251 KAWTN--SEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKV 313
            .|:.|  ||   .::|:|.:|:......:.|:..|.::|:.|.|||..|:...||:.....|  |
  Fly   329 AAFRNRASE---DNEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRMSSGLFAKL--V 388

Human   314 AHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
            .|...:.|:|:||.|.|.|.....::.:  .|:|..:.||.:.|....|..:||.|:..:|
  Fly   389 VHSTKIIVDEQGTTAGAVTEAALANKAT--PPKFLLNRPFQYMIVEKATGLLLFAGQVRNP 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	103/384 (27%)
Spn77Ba	NP_649205.3	serpin77Ba-like_insects	72..447	CDD:381062	103/384 (27%)