Protein Alignment SERPINB8 and Spn42Db

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_610244.2
• Gene: Spn42Db / 35599
• FlyBaseID: FBgn0033112
• Length: 388
• Species: Drosophila melanogaster
• Alignment Length: 370
• Identity: 112/370 - (30%)
• Similarity: 185/370 - (50%)
• Gaps: 18/370 - (4%)

Human    11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMG-AKGS-TAAQMSQALCL--YKDGDIHRGFQ 71
            ||:.|...|.......|:.:||:||..:.||:.|| ::|| ||.:|.:.|..  .:...:...|.
  Fly    13 FALCLHDHLCRASAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLEAQQVAESFG 77

Human    72 SLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWV 136
            .:|....:.   .:|:.||.|:..|.......|....::.::::..|:.|.  :|:....||.||
  Fly    78 VVLKSYEQC---QVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDFG--SEQAASIINKWV 137

Human   137 AEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKTVQMMFKEA 201
            ..:|...|.:::....:...::|.|||.|:|||:|:..|:.|.||...|..::....|:||....
  Fly   138 ESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFKGEWSISFNEKETREEDFFGSDRPTRVRMMHVCE 202

Human   202 KFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQV 266
            .|............|.:.|....|:|:|||||:.::|..:||.|:....:..:::..|  .||.|
  Fly   203 NFFFAVLPMFEATALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNL--EKVDV 265

Human   267 FLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGM-STEKNVPLSKVAHKCFVEVNEEGTEAAA 330
            .:|....|...:|...|..:||...| ..:|:..|| .:|:::.:|::.||.|:|:||.||||||
  Fly   266 KIPSFTAEFQQELSQVLMLMGMNRIF-SGQAELGGMLQSEESLFVSQIVHKAFIEINEVGTEAAA 329

Human   331 ATAVVRNSRC--SRMEPR--FCADHPFLFFIRHHKTNCILFCGRF 371
            |||.|...|.  :|..|.  |.|:.||.:.|:.: |:.:||.|.|
  Fly   330 ATAAVATFRSMPARQGPPKVFHANRPFFYAIKDN-THGLLFAGHF 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	112/370 (30%)
Spn42Db	NP_610244.2	serpin42Da-like	9..372	CDD:381065	110/367 (30%)