Protein Alignment SERPINB8 and Spn31A

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 358
• Identity: 98/358 - (27%)
• Similarity: 170/358 - (47%)
• Gaps: 27/358 - (7%)

Human    26 RNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYK----DGDIHRGFQSLLSEVNRTGTQYLL 86
            :||..||:.:.:.|:::|:|:.|:||.::.:.|.|.:    :..:...:.:.|..:. |.....|
  Fly    29 QNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMANFYAAELGNIT-TDADTFL 92

Human    87 RTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWV-AEKTEGKISEVLDA 150
            :..|||..........||::..|.::.|..|.:.. |.||:.|:||::.: |....|...::..|
  Fly    93 QLQNRLMLSSESGVADDFQKIAQTYFHATAECVDL-EQTEKLRRHISEQILASVGGGSWKDIHVA 156

Human   151 GTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGML-FKTNEEKKTVQMMFKEAKF-KMGYADEVHT 213
            |.....|.|:|: |...:.||...|. .|..|:. |.:..:.|:|.|:|.:..| |.....::..
  Fly   157 GGSSANTLLLLL-AANLQSKWFLPFS-AYRTGLYEFHSGSQVKSVPMLFDDDMFVKFAELRDLDA 219

Human   214 QVLELPYVE-EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESY 277
            :.:||||.. |||||:::||:....|..:||.|  .........:::....|||.||:..::...
  Fly   220 RAIELPYEHAEELSMLLILPNQRGGLQELEKQL--HDLDLGALQQRMQMEGVQVLLPKFSIDFEC 282

Human   278 DLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAA-----AT----A 333
            .|...|::||..:.| .|.|:|..:....|:|::.|..|..:.:||.|:.:..     ||    .
  Fly   283 SLRQPLKQLGFEEIF-AASANFKHLHASANLPIADVLQKLRINLNESGSGSGPELPKNATEYKPI 346

Human   334 VVRNSRCSRMEPRFCADHPFLFFIRHHKTNCIL 366
            |:.||...:.   |.|||||.|.||......::
  Fly   347 VISNSSRQKF---FRADHPFFFAIRSENVTYLM 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	98/358 (27%)
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	98/358 (27%)