Protein Alignment SERPINB8 and Spn28B

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_609128.2
• Gene: Spn28B / 34035
• FlyBaseID: FBgn0083141
• Length: 378
• Species: Drosophila melanogaster
• Alignment Length: 367
• Identity: 109/367 - (29%)
• Similarity: 188/367 - (51%)
• Gaps: 20/367 - (5%)

Human    16 FKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD-IHRGFQSLLSEVNR 79
            ::||..::..||:.:||:|....::||:|.:.|.|..::...|...::.. :...::||||::.|
  Fly    22 YRILASQNAKRNLIYSPISAEIIMSMVYMASGGKTFEELRNVLKFSENKTLVANNYRSLLSDLKR 86

Human    80 TGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKI 144
            ..|..:|..|||::..|....:|:|.:..:|.::|:.:.:.. :|.......:|.|:..:|.|.|
  Fly    87 RETFIILHMANRIYVNKKYCLVPEFNQLARKAFKAKAKSIRL-DDPVSASAIVNSWILNRTRGMI 150

Human   145 SEVLDAGTVDPLTKLVLVNAIYFKGKW--NEQFDRKYTRGMLFKTNEEKKTVQMMFKEAKFKMGY 207
            ..::.....:..|...|||||||||:|  |.:.|:.:........| |...|:||...|....||
  Fly   151 RNIVLPKDFNSDTSAFLVNAIYFKGQWLYNFKADQTHIADFYVSAN-EIIPVKMMTLSASLLSGY 214

Human   208 ADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLK 272
            .|::..:::||||....|||.|:||:....|..:::.:.:..:       .|.|..|.|.||:.|
  Fly   215 IDDIDAKIIELPYWNSTLSMRIILPNSVDGLRKLKEKVGFIDY-------HLEKKSVNVKLPKFK 272

Human   273 LEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVV-- 335
            :|....|:.....||::|.| :..||.:|:..|....:.|:..|.|::::|:|.||:|||.|:
  Fly   273 IESKAQLKGIFENLGILDVF-KPSADLNGLVLESGAKIDKIVQKAFLKIDEKGGEASAATGVLTR 336

Human   336 -RNSRCSRMEP--RFCADHPFLFFIRHHKTNCILFCGRFSSP 374
             :.|..:.::|  .|.|||||.:.|  |....|.|.|....|
  Fly   337 RKKSIDNLIQPPMEFIADHPFFYVI--HDNKVIYFQGHIVEP 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	108/365 (30%)
Spn28B	NP_609128.2	serpin42Dd-like_insects	12..376	CDD:381070	108/365 (30%)