Protein Alignment SERPINB8 and Spn75F

DIOPT Version :10

• Sequence 1: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_001036614.1
• Gene: Spn75F / 317912
• FlyBaseID: FBgn0052203
• Length: 356
• Species: Drosophila melanogaster
• Alignment Length: 312
• Identity: 76/312 - (24%)
• Similarity: 136/312 - (43%)
• Gaps: 34/312 - (10%)

Human    11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGDIHRGFQSLLS 75
            |.|:|.|.|.:...:||..:||::|..||.::::.....|..|:..||.|  .|.......||..
  Fly    22 FEINLTKQLSKGRLARNFVYSPIAIRQALGLLYLSKDNVTDQQLESALQL--TGLNQEEIISLFK 84

Human    76 EVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAED---TEECRKHINDWVA 137
            |......|......||::.....:..|:..:..:.. ..|::.::|:.|   ..|.:|.:|.|:.
  Fly    85 EAREKVAQEQFTMGNRIYLSPDYNASPNITQLSENL-GVEVKNMTFSGDQSAASEIKKWLNKWIG 148

Human   138 EKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQ----FDRKYTRGMLFKTNEEK--KTVQM 196
             |..|.:   .....:...|::|.|..:.:...|..:    .:|.:|   |.:.|::.  .|.||
  Fly   149 -KAGGNL---FGKNDISQTTQIVAVQGMSYSCVWKNRETALTNRTFT---LLRQNKKPFVYTTQM 206

Human   197 MFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL-TYEKFKAWTNSEKLT 260
            |:.||.......|:|  :.:.:|:...::.|::|||........:..:| |..|.       ||.
  Fly   207 MYTEAPMDFFNNDQV--RGVMVPFKNSDMGMLVLLPRPRYSTQQILYSLDTILKI-------KLR 262

Human   261 KS-KVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKA----DFSGMSTEKN 307
            :| |..:|||:.|:.||.||...|:.||:.:.|....|    .::....::|
  Fly   263 RSKKTHLFLPKFKVSESVDLNMALKALGIQNLFTNTNAANFKQYNSFDADQN 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	76/312 (24%)
Spn75F	NP_001036614.1	serpin	20..352	CDD:381000	76/312 (24%)