Protein Alignment ATP6V0C and Vha16-3

DIOPT Version :10

• Sequence 1: NP_001685.1
• Gene: ATP6V0C / 527
• HGNCID: 855
• Length: 155
• Species: Homo sapiens
• Sequence 2: NP_729706.1
• Gene: Vha16-3 / 317846
• FlyBaseID: FBgn0028667
• Length: 158
• Species: Drosophila melanogaster
• Alignment Length: 242
• Identity: 48/242 - (19%)
• Similarity: 83/242 - (34%)
• Gaps: 90/242 - (37%)

Human     2 FSWLLRLCQKENGDEGETRPTEKEEGILSHEKGRRKSFLRRHRSA---RNTSTQN--------SK 55
            |:|:||..|..       |..:...|:   .:|.:|....|:..|   .|:|.:|        .|
  Fly     4 FNWVLRHVQAR-------RTFDSAIGL---RQGSQKPLFERYIHATGINNSSARNYYDVLGVSPK 58

Human    56 MTKKRSK--INELEE------------LKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNII 106
            .|::..|  .:||.:            .|...::|....|.:........|:.|.||.:...|..
  Fly    59 ATREEIKKSFHELAKKFHPDTNRNNPSAKRKFQEIREAYETLGNSERREEYDKLQYRNSDYVNND 123

Human   107 KSQHEKTMLDMDKMTQSIIISMKFSE-------ELLKDNYSYSIKQKHRLRECTQLKEKVRILLN 164
            ....|:    ..:..||     .||:       |:.::|               |:|..:|:.|:
  Fly   124 GGDSER----FRRAYQS-----NFSDTFHKIFSEIFENN---------------QIKPDIRVELS 164

Human   165 ENRKLLVEQAGTQVSHGEEKR-------FCE---------EASKNIC 195
                |.:.:|    :.|..||       ||:         :|:.:||
  Fly   165 ----LSLSEA----AEGCTKRLSFDAYVFCDSCDGLGHPSDAAMSIC 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V0C	NP_001685.1	V_ATP_synt_C	13..118	CDD:130170	23/129 (18%)
		ATP-synt_Vo_c_ATP6C_rpt2	86..153	CDD:349416	12/73 (16%)
Vha16-3	NP_729706.1	V_ATP_synt_C	16..121	CDD:130170	20/107 (19%)
		ATP-synt_Vo_c_ATP6C_rpt2	91..156	CDD:349416	15/88 (17%)