Protein Alignment SERPINB5 and Spn88Eb

DIOPT Version :9

• Sequence 1: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Sequence 2: NP_650427.1
• Gene: Spn88Eb / 41829
• FlyBaseID: FBgn0038299
• Length: 426
• Species: Drosophila melanogaster
• Alignment Length: 398
• Identity: 100/398 - (25%)
• Similarity: 186/398 - (46%)
• Gaps: 50/398 - (12%)

Human    11 FAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFE---NVKDVPFGFQT 72
            |::.|.||:.|..|.||:.|||.....:|.||...:...|..|:.|.|:..   |.:.|...: |
  Fly    41 FSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSY-T 104

Human    73 VTSDVNKL---SSFYSLKLIKRLYVDKSLNLSTEF----ISSTKRPYAKELETVDFKDKLEETKG 130
            :....::.   .|...|....|::||:::|:|.:|    ..:||.        :|||:..|....
  Fly   105 LAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTLLYGATKE--------LDFKNDPETGLK 161

Human   131 QINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPV 195
            :||:.|.|.|.....::|:...:...|.:::.||||..|:|:.:|...||...||.:|:.:.:.|
  Fly   162 EINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMV 226

Human   196 QMMNMEATFCMGNIDSINCKIIELPFQ---------------NKHLSMFILLPKDVEDESTGLEK 245
            .||:....|.|...:.:..:||:||::               ...:||.|:||   ......|.:
  Fly   227 YMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILP---NSNKISLNR 288

Human   246 IEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSET 310
            :..:||::|:.:|...:  ...|::||:|||:.|:.::....|..:|:..:|:.:.:.....::.
  Fly   289 VISRLNADSVKKWFERA--LPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTADP 351

Human   311 KGVALSNVIHKVCLEITEDGGDSIEVPGARIL------QHKD--ELNADHPFIYIIRHNKTRNII 367
            ..:.:.:..|...:::.|.|..:   ..|.||      :..|  :.|.:|||:::|...|...|:
  Fly   352 ISLVIDDAQHLAKIKVDEVGSTA---AAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTIL 413

Human   368 FFGKFCSP 375
            |.|.:..|
  Fly   414 FAGVYSDP 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINB5	NP_002630.2	maspin_like	4..375	CDD:239012	99/396 (25%)
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	99/393 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920