Protein Alignment SERPINA4 and Spn42Dd

DIOPT Version :9

• Sequence 1: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 116/389 - (29%)
• Similarity: 172/389 - (44%)
• Gaps: 65/389 - (16%)

Human   100 YYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHT 164
            |.|::.....:|:..||:||....:|:.:||...:..::...||  |....:..|...:..||:.
  Fly    22 YQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALG--LPSEDKEAVAARYGALLND 84

Human   165 LNLPGHGLETRVGSALFLSHNLKFLAKFLND--------TMAVYEAKLFHTNFYDTVGTIQL--- 218
            |    .|.|.  |..|.|::.:     ::||        .:||.|.      |.....:|.|
  Fly    85 L----QGQEE--GPILKLANRI-----YVNDQYSLNQNYNLAVREP------FKSEAESISLTNG 132

Human   219 ------INDHVKKETRGKIVDLV--SELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDEN 275
                  ||..|..:|.|||..::  ..:..||..:|||.||||..||..|..::|....|.|..|
  Fly   133 PVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTAN 197

Human   276 TTVRVPMMLQDQEHHW-YLHDRYLPCSVLRMDY-KGDATVFFILPNQGKMREIEEV-LTPEMLMR 337
            .:|.|.||.|...... |..|  |...|:.:.| ..:.::...||     ||:|.: ...|.::.
  Fly   198 KSVPVQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLP-----REVEGLSALEEKIVG 255

Human   338 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGI-TKQQKLEASKSFH 401
            :...|..:..|    |.||||.|.....|.:.|.:||..:||:..:||||: ..:...:.|:..|
  Fly   256 FARPLVAKEVY----LKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSH 316

Human   402 KATLDVDEAGTEAAAATSFAIKFFSAQTNR----HILRFNRPFLVVIFSTSTQSVLFLGKVVDP 461
            ||.|:|:|.|.|||.|||.|:      |||    ..|..:.||..||...:|  :.|.|:||.|
  Fly   317 KAFLEVNEEGAEAAGATSVAV------TNRAGFSTFLMADHPFAFVIRDANT--IYFQGRVVSP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINA4	NP_001275961.1	alpha-1-antitrypsin_like	91..458	CDD:239011	113/384 (29%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	113/384 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020